Alternatives to canagliflozin
3 same-class SPL records vs canagliflozin - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Invokana
About canagliflozin
Invokana is a medicine used with diet and exercise to lower blood sugar in adults with type 2 diabetes. It can also help reduce the risk of heart problems and kidney disease in some patients.
Used for: Invokana is used to help control blood sugar levels in adults with type 2 diabetes. It is used along with diet and exercise. Invokana can also lower the risk of major heart problems like heart attack and stroke in adults with both type 2 diabetes and heart disease. It can also reduce the risk of kidney failure, heart-related death, and hospitalization for heart failure in adults with type 2 diabetes and kidney problems.
3 SGLT2 Inhibitor peers (wide set)
dapagliflozin
RxFarxiga
This medicine can help adults with chronic kidney disease by reducing the risk of kidney problems, heart problems, and needing to go to the hospital for heart failure. It can also help adults with heart failure by reducing the risk of heart problems and needing urgent care for heart failure. For adults with type 2 diabetes, it can help lower the risk of needing to go to the hospital for heart failure.
empagliflozin
RxJardiance
ertugliflozin
RxSteglatro
canagliflozin vs dapagliflozin & empagliflozin · FAERS reaction fields
FAERS top-reaction field "Toe Amputation" shows the widest count spread between canagliflozin and dapagliflozin, empagliflozin, ertugliflozin in this extract (2,195-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | canagliflozin | dapagliflozin | empagliflozin | ertugliflozin |
|---|---|---|---|---|
| Diabetic Ketoacidosis | 3,421 | 1,524 | 3,773 | 51 |
| Toe Amputation | 2,195 | - | - | - |
| Osteomyelitis | 2,163 | - | - | - |
| Acute Kidney Injury | 1,990 | 1,699 | 1,599 | - |
| Fungal Infection | 1,446 | 1,352 | 2,057 | 58 |
| Weight Decreased | 1,340 | 1,827 | 2,749 | - |
| Blood Glucose Increased | 1,227 | 1,861 | 3,043 | 46 |
| Gangrene | 1,084 | - | - | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
canagliflozin peer mix vs class inventory
Peer mix
0 OTC and 3 Rx SPL records in this peer set (3 total). Class inventory for SGLT2 Inhibitor: 4 drugs.
Frequently Asked Questions
What same-class SPL records sit beside canagliflozin? ▼
Reading a wide SGLT2 Inhibitor peer set (3 records)
canagliflozin (Invokana) sits in a wide SGLT2 Inhibitor peer set (3 of 3 class peers shown). Labeled indication field for canagliflozin: Invokana is used to help control blood sugar levels in adults with type 2 diabetes.
Top FAERS reaction fields for canagliflozin total 16,917 reports across 10 reactions, set beside dapagliflozin, empagliflozin, ertugliflozin. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for canagliflozin: see also the generic vs brand label guide when reading Invokana SPL strings.
Read our methodology - how this data is sourced, computed, and verified.