Alternatives to amphotericin B
FDA shortage status is active for amphotericin B; 1 same-class SPL records are listed below for registry comparison only.
Brand: Ambisome, Fungizone
amphotericin B class peers while FDA lists an active shortage
amphotericin B (Ambisome, Fungizone) is on an FDA shortage listing while 1 other Polyene Antifungal SPL records remain in this registry peer set (class inventory 2). Labeled indication field for amphotericin B: This medicine treats fungal infections like aspergillosis, candidiasis, and cryptococcosis.
Top FAERS reaction fields for amphotericin B total 6,391 reports across 10 reactions, set beside nystatin. Counts are exposure-weighted submissions, not per-patient risk.
About amphotericin B
Amphotericin B liposome is an antifungal medicine. It fights serious fungal infections in your body.
Used for: This medicine treats fungal infections like aspergillosis, candidiasis, and cryptococcosis. It can also treat cryptococcal meningitis in people with HIV. It may also be used for visceral leishmaniasis, but this infection can return, especially in those with weak immune systems.
1 Polyene Antifungal peers (wide set)
amphotericin B vs nystatin · FAERS reaction fields
FAERS top-reaction field "Condition Aggravated" shows the widest count spread between amphotericin B and nystatin in this extract (841-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | amphotericin B | nystatin |
|---|---|---|
| Pyrexia | 972 | 1,110 |
| Condition Aggravated | 841 | - |
| Febrile Neutropenia | 650 | - |
| Acute Kidney Injury | 625 | 957 |
| Sepsis | 613 | - |
| Pneumonia | 576 | 1,613 |
| Hypokalaemia | 542 | - |
| Multiple Organ Dysfunction Syndrome | 528 | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
amphotericin B shortage vs Polyene Antifungal peer index
Shortage status
FDA shortage listing is active for amphotericin B (status: To Be Discontinued). Peer rows remain a registry index, not a switch guide.
Frequently Asked Questions
Does FDA list a shortage for amphotericin B while peers remain indexed? ▼
Registry note: Shortage listings and peer indexes are for registry orientation only. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for amphotericin B: see also the generic vs brand label guide when reading Ambisome SPL strings.
Read our methodology - how this data is sourced, computed, and verified.