FDA Drug Shortage Database
Lidocaine (Xylocaine) shortage
The FDA Drug Shortage Database lists 15 of 51 lidocaine presentations as limited or unavailable (updated October 6, 2026); the first entry was posted on February 22, 2012. 34 more presentations are on the list as available.
- Generic listed
- In shortage
Check it at the source: the FDA Drug Shortage Database.
Which strengths are short?
| Strength | Limited or unavailable now | Listed now, available | Resolved or discontinued |
|---|---|---|---|
| 000mg/50ml injection | 0 | 1 | 0 |
| 1% injection | 0 | 0 | 1 |
| 2% injection | 0 | 0 | 1 |
| 4mg/1ml injection | 0 | 1 | 0 |
| 8mg/1ml injection | 0 | 1 | 0 |
| 10mg/1ml injection | 5 | 5 | 0 |
| 10mg/ml injection | 1 | 1 | 0 |
| 15mg/1ml injection | 2 | 0 | 0 |
| 20mg/1ml injection | 4 | 3 | 0 |
| 20mg/2ml injection | 0 | 2 | 0 |
| 20mg/ml injection | 2 | 2 | 0 |
| 40mg/2ml injection | 0 | 1 | 0 |
| 50mg/5ml injection | 0 | 3 | 0 |
| 100mg/10ml injection | 0 | 1 | 0 |
| 100mg/5ml injection | 0 | 2 | 0 |
| 200mg/10ml injection | 0 | 1 | 0 |
| 200mg/20ml injection | 0 | 2 | 0 |
| 200mg/5ml injection | 0 | 1 | 0 |
| 250mg/50ml injection | 1 | 1 | 0 |
| 300mg/20ml injection | 0 | 1 | 0 |
| 300mg/30ml injection | 0 | 2 | 0 |
| 400mg/20ml injection | 0 | 1 | 0 |
| 500mg/50ml injection | 0 | 2 | 0 |
Which presentations are listed?
Limited or unavailable now (15)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Lidocaine Hydrochloride In Plastic Container, Injection, 250 mg/50 mL (0.5%; 5 mg/mL) (NDC 0409-4275-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride Preservative Free, Injection, 20 mg/1 mL (NDC 63323-208-05) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated September 15, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-159-74) | Eugia US LLC | Current posted February 20, 2018, updated October 2, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-161-02) | Eugia US LLC | Current posted February 20, 2018, updated October 2, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 63323-201-10) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated October 6, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 65282-1605-1) | Spectra Medical Devices, LLC | Current posted June 14, 2018, updated May 15, 2026 | Unavailable; Other |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 73293-0001-2) | Huons Co., Ltd. (South Korea) | Current posted July 14, 2018, updated July 30, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 10 mg/mL (NDC 55150-251-10) | Eugia US LLC | Current posted June 13, 2018, updated October 2, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 55150-165-05) | Eugia US LLC | Current posted February 20, 2018, updated October 2, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 76329-3390-1) | Amphastar Pharmaceuticals, Inc. | Current posted February 22, 2012, updated September 16, 2026 | Limited Availability; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-254-10) | Eugia US LLC | Current posted June 13, 2018, updated October 2, 2026 | Unavailable; Demand increase for the drug |
| Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-256-50) | Eugia US LLC | Current posted June 13, 2018, updated October 2, 2026 | Unavailable; Demand increase for the drug |
| Xylocaine, Injection, 15 mg/1 mL (NDC 63323-493-91) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated October 6, 2026 | Unavailable; Demand increase for the drug |
| Xylocaine, Injection, 15 mg/1 mL (NDC 63323-493-97) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated October 6, 2026 | Unavailable; Demand increase for the drug |
| Xylocaine, Injection, 20 mg/1 mL (NDC 63323-496-97) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated October 6, 2026 | Unavailable; Demand increase for the drug |
Listed now, available (34)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Lidocaine Hydochloride, Injection, 50 mg/5 mL (NDC 83634-653-05) | Anthea Pharma | Current posted February 22, 2012, updated October 5, 2026 | Available |
| Lidocaine Hydrochloride And Dextrose, Injection, 4 mg/1 mL (NDC 0338-0409-03) | Baxter Healthcare | Current posted October 25, 2017, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride And Dextrose, Injection, 8 mg/1 mL (NDC 0338-0411-02) | Baxter Healthcare | Current posted October 25, 2017, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride In Plastic Container, Injection, 1,000 mg/50 mL (2%; 20 mg/mL) (NDC 0409-4277-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride In Plastic Container, Injection, 10 mg/1 mL (NDC 63323-201-02) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated October 6, 2026 | Available |
| Lidocaine Hydrochloride In Plastic Container, Injection, 200 mg/20 mL (1%; 10 mg/mL) (NDC 0409-4276-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride In Plastic Container, Injection, 400 mg/20 mL (2%; 20 mg/mL) (NDC 0409-4277-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride In Plastic Container, Injection, 500 mg/50 mL (1%; 10 mg/mL) (NDC 0409-4276-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride Preservative Free In Plastic Container, Injection, 100 mg/5mL (2%,20 mg/1 mL) Syringes (NDC 0409-1323-05) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride Preservative Free In Plastic Container, Injection, 50 mg/5mL (1%, 10 mg/1 mL) Syringes (NDC 0409-9137-05) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride Preservative Free, Injection, 20 mg/2 mL (1%; 10 mg/mL) (NDC 0409-4713-32) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride Preservative Free, Injection, 200 mg/5 mL (4%; 40 mg/mL) (NDC 0409-4283-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride Preservative Free, Injection, 300 mg/20 mL (1.5%; 15 mg/mL) (NDC 0409-4776-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride Preservative Free, Injection, 50 mg/5 mL (1%; 10 mg/mL) (NDC 0409-4713-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 0143-9577-10) | Hikma Pharmaceuticals USA, Inc. | Current posted June 13, 2018, updated September 18, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-162-05) | Eugia US LLC | Current posted February 20, 2018, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 10 mg/1 mL (NDC 55150-163-30) | Eugia US LLC | Current posted February 20, 2018, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 10 mg/mL (NDC 55150-252-20) | Eugia US LLC | Current posted June 13, 2018, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 100 mg/10 mL (NDC 83634-651-10) | Anthea Pharma | Current posted February 22, 2012, updated October 5, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 100 mg/5 mL (2%; 20 mg/mL) (NDC 0409-2066-05) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 0143-9575-10) | Hikma Pharmaceuticals USA, Inc. | Current posted June 13, 2018, updated September 18, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 20 mg/1 mL (NDC 63323-202-02) | Fresenius Kabi USA, LLC | Current posted February 22, 2012, updated October 6, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 20 mg/2 mL (NDC 83634-653-02) | Anthea Pharma | Current posted February 22, 2012, updated October 5, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-164-02) | Eugia US LLC | Current posted February 20, 2018, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 20 mg/mL (NDC 55150-255-20) | Eugia US LLC | Current posted June 13, 2018, updated October 2, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 200 mg/10 mL (2%; 20 mg/mL) (NDC 0409-4282-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 200 mg/20 mL (NDC 83634-651-20) | Anthea Pharma | Current posted February 22, 2012, updated October 5, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 250 mg/50 mL (0.5%; 5 mg/mL) (NDC 0409-4278-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 300 mg/30 mL (1%; 10 mg/mL) (NDC 0409-4279-02) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 300 mg/30 mL (NDC 83634-653-30) | Anthea Pharma | Current posted February 22, 2012, updated October 5, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 40 mg/2 mL (2%; 20 mg/mL) (NDC 0409-4282-01) | Hospira, Inc., a Pfizer Company | Current posted February 22, 2012, updated September 22, 2026 | Available |
| Lidocaine Hydrochloride, Injection, 500 mg/50 mL (NDC 83634-651-50) | Anthea Pharma | Current posted February 22, 2012, updated October 5, 2026 | Available |
| Lidocaine Hydrochloride, Preservative Free, Injection, 10 mg/1 mL (NDC 0143-9595-25) | Hikma Pharmaceuticals USA, Inc. | Current posted June 13, 2018, updated September 18, 2026 | Available |
| Lidocaine Hydrochloride, Preservative Free, Injection, 20 mg/1 mL (NDC 0143-9594-25) | Hikma Pharmaceuticals USA, Inc. | Current posted June 13, 2018, updated September 18, 2026 | Available |
Resolved or discontinued (2)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Lidocaine Hydrochloride, Injection, 1%, USP (For Cardiac Use Only) 50 mg/5 mL (10 mg/mL) LifeShield™ ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4904-34)" | Hospira, Inc., a Pfizer Company | To Be Discontinued posted November 7, 2025, updated November 7, 2025 | not given |
| Lidocaine Hydrochloride, Injection, 2%, USP (For Cardiac Use Only) 100 mg/5 mL (20 mg/mL) LifeShield® ABBOJECT® Glass Syringe (20 G x 1 1/2) (NDC 0409-4903-34)" | Hospira, Inc., a Pfizer Company | To Be Discontinued posted November 7, 2025, updated November 7, 2025 | not given |
Source: FDA Drug Shortage Database via openFDA, read October 8, 2026
Are medicines for the same conditions short too?
Medicines whose labels share an indication with this one, and their own shortage status; listed as records, not substitutes.
| Medicine | Shared indication | Shortage | Generic labelers | Pharmacy cost |
|---|---|---|---|---|
| Menthol | Pain | No current entry | none listed | $0.0424 per unit 5.8 mg |
| Diclofenac | Pain | A presentation being discontinued | 149 labelers | $0.0619 per tablet 75 mg tablet |
| Bacitracin and neomycin and polymyxin b | Pain | No current entry | 1 labeler | $0.111 per gram Triple antibiotic ointment |
| Menthol and methyl salicylate | Pain | No current entry | none listed | $0.0365 per gram 15%-10% cream |
| Capsaicin | Pain | No current entry | none listed | $0.207 per gram 0.1% cream |
| Benzocaine | Pain | No current entry | none listed | n/a |
| Witch hazel | Pain | No current entry | none listed | $0.0435 per unit 50% pad |
| Camphor | Pain | No current entry | none listed | $0.0188 per mL Vapor steam liquid |
| Methyl salicylate | Pain | No current entry | none listed | n/a |
| Pramoxine | Pain | No current entry | none listed | $0.0403 per mL 1% cleanser |
| Phenol | Pain | No current entry | none listed | $0.0124 per mL 1.4% spray |
| Tetracaine | Pain | No current entry | 2 labelers | $4.33 per mL 0.5% eye drop |
Source: FDA drug labels, FDA Drug Shortage Database, NDC Directory, CMS NADAC of October 7, 2026 (FDA files October 8, 2026)
What next?
- Every shortage now
- medicines by presentations in shortage