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Over-the-counter medicine

Witch hazel

Witch hazel is an over-the-counter medicine. No generic is listed; pharmacies paid $0.0435 per unit (Hemorrhoidal medicated 50% pad) in the October 7, 2026 NADAC survey.

  • No generic listed
  • Over the counter

Check it at the source: the witch hazel FDA label on DailyMed (effective September 3, 2026); every witch hazel label on DailyMed.

Highlights of the record

FDA label of September 3, 2026; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026

Used for

From the label: indications and usage

helps relieve the local itching and discomfort associated with hemorrhoids temporary relief of irritation and burning aids in protecting irritated anorectal areas

Forms and strengths

  • 0.5 g
  • 2 g
  • 5 g
  • 50 mg
  • 200 mg
  • 500 mg
  • 0.4 g/ml
  • 0.5 g/g
  • 0.5 mg/ml
  • 3.36 g/28g
  • 50 g/100g
  • 50 g/100ml

Liquid; cloth; solution; patch; swab.

On the market

Generic approvals
No generic approved
Labelers listed (NDC)
72 of which 0 under generic applications, 0 under brand applications, repackagers included

Supply and safety

Pharmacy cost (NADAC)
$0.0435 per unit Hemorrhoidal medicated 50% pad
Shortage (FDA)
No current entry
Recalls by its makers (FDA)
No recall recorded
FAERS reports
166 through July 30, 2026

What is witch hazel used for?

From the label: indications and usage

helps relieve the local itching and discomfort associated with hemorrhoids temporary relief of irritation and burning aids in protecting irritated anorectal areas

Conditions named in the indications of witch hazel's FDA labels, with every medicine labeled for each:

From other witch hazel labels

Pain: Uses Helps relieve pain and swelling from hemorrhoids and childbirth.

Source: FDA drug label (KROGER MEDICATED WIPES HEMORRHOIDAL WIPE WITH WITCH HAZEL AND ALOE), The Kroger Co., effective September 3, 2026 (SPL set 48c1598d-6667-446f-ac90-10ab945d0617), via openFDA; the full label on DailyMed

Is there a generic for witch hazel?

No generic witch hazel is approved (Drugs@FDA, October 8, 2026).

Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)

What do pharmacies pay for witch hazel?

In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.0435 per unit (Hemorrhoidal medicated 50% pad), up 13% from $0.0384 on October 8, 2025. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.

  • Ft witch hazel 86% solution (generic)
$0.0076
$0.0056
April 2024October 2026
NADAC per unit, October 7, 2026
Strength and formBrand or genericPharmacy cost30 tablets, or one pen or vial12-month change
Ft witch hazel 86% solutionGeneric$0.0076 per mLn/a+14%
Gnp witch hazel 86% solutionGeneric$0.0076 per mLn/a+14%
Hemorrhoidal medicated 50% padGeneric$0.0435 per unitn/a+13%
Medi-pads 50%Generic$0.0435 per unitn/a+13%
Qc medicated cooling 50% padsGeneric$0.0435 per unitn/a+13%
Witch hazel 86% solutionGeneric$0.0076 per mLn/a+14%

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What do FAERS reports show for witch hazel?

The FDA Adverse Event Reporting System holds 166 reports that list witch hazel among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 10 are coded as a death and 58 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

The most reported reactions

  • Drug Ineffective (a use or a product term, not a reaction)15
  • Headache15
  • Nausea13
  • Erythema12
  • Rectal Haemorrhage11
  • Skin Burning Sensation11
  • Fatigue10
  • Inappropriate Schedule Of Product Administration (a use or a product term, not a reaction)10

Side effects: the label's list and every FAERS reaction

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026

What else is labeled for the same conditions as witch hazel?

14 other medicines are given the same way (topical) and in the same FDA class as witch hazel or labeled mainly for the same use (pain), the same class first. Pain lists all 80 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.

MedicineShared indicationGeneric labelers (topical)Pharmacy costShortage
LidocainePain56 labelers$0.154 per gram 5% ointmentIn shortage
MentholPainnone listed$0.0557 per mL 4% gelNo current entry
DiclofenacPain103 labelers$0.0813 per gram 1% gelA presentation being discontinued
Bacitracin and neomycin and polymyxin bPainnone listed$0.111 per gram Triple antibiotic ointmentNo current entry
Menthol and methyl salicylatePainnone listed$0.0365 per gram 15%-10% creamNo current entry
CapsaicinPainnone listed$0.207 per gram 0.1% creamNo current entry
BenzocainePainnone listedn/aNo current entry
CamphorPainnone listed$0.048 per mL Camphor spiritNo current entry

Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)

How does witch hazel compare with medicines for the same use?

1 side-by-side page set witch hazel beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.

What next?

Witch hazel side effects
the label's list beside FAERS reports
Check an interaction
what two or more labels say about each other