Theophylline and Nadolol Interaction
Drug interaction information between Theophylline and Nadolol.
Theophylline and Nadolol have a documented major interaction in FDA labeling.
FDA drug labeling documents a major-severity interaction between Theophylline and Nadolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Nadolol is a beta-blocker that can block the airway-opening effects of theophylline, which may make it harder for you to breathe.
FDA Label Information
albuterol, systemic and inhaled mebendazole amoxicillin medroxyprogesterone ampicillin, with or without sulbactam methylprednisolone atenolol metronidazole azithromycin metoprolol caffeine, dietary ingestion nadolol cefaclor nifedipine co-trimoxazole (trimethoprim and sulfamethoxazole) nizatidine diltiazem norfloxacin dirithromycin ofloxacin enflurane omeprazole famotidine prednisone, prednisolone felodipine ranitidine finasteride rifabutin hydrocortisone roxithromycin isoflurane Sorbitol (purgative doses do not inhibit theophylline absorption) isoniazid sucralfate isradipine terbutaline,...
Theophylline Also Interacts With
- Metoprolol major
- Albuterol major
- Omeprazole major
- Amoxicillin major
- Famotidine major
Frequently Asked Questions
What SPL severity band is on file for Theophylline + Nadolol?
Compiled FDA labeling labels this pair major. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Theophylline has 86 labeled pairs on file vs Nadolol's 3. In the major band specifically: Theophylline has 27 (also Metoprolol, Albuterol, Omeprazole, Amoxicillin); Nadolol has 1.
What mechanism field is on file for Theophylline and Nadolol?
Nadolol is a beta-blocker that can block the airway-opening effects of theophylline, which may make it harder for you to breathe.
Theophylline carries more major-labeled pairs than Nadolol
SPL source-record counts only. This page's band is major · classes on file: Theophylline (Methylxanthine Bronchodilator); Nadolol (Non-Selective Beta-Blocker).
Theophylline has 27 major-labeled pairs vs Nadolol's 1.
27 major · 5 moderate · 54 minor · 86 total
- Other major peers for Theophylline
- Metoprolol
- Albuterol
- Omeprazole
- Amoxicillin
1 major · 0 moderate · 2 minor · 3 total
Nadolol has no other major-band peer in this dataset besides Theophylline.
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.