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What the FDA labels say about taking them together

Terazosin and verapamil

Terazosin's FDA label (Tezruly) of April 18, 2025 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name terazosin. The terazosin label: “… with other anti-hypertensive agents, especially the calcium channel blocker verapamil, can increase the risk of hypotension.”

Check it at the source: the terazosin FDA label on DailyMed (effective May 5, 2026, Jubilant Cadista Pharmaceuticals Inc.); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).

What does the terazosin label say about verapamil?

Tezruly label (ANI Pharmaceuticals, Inc., April 18, 2025), drug interactions

DRUG INTERACTIONS Co-administration of verapamil with terazosin increases the systemic exposure of terazosin [see Clinical Pharmacology (12.3)], which may increase the risk of hypotenstion.

Tezruly label (ANI Pharmaceuticals, Inc., April 18, 2025), warnings and precautions

Hypotension with Concomitant Use of Other Antihypertensive Agents and Phosphodiesterase Type 5 Inhibitors (PDE5-I) Concomitant use of TEZRULY with other anti-hypertensive agents, especially the calcium channel blocker verapamil, can increase the risk of hypotension.

Source: FDA drug label (Tezruly, NDA218139), ANI Pharmaceuticals, Inc., effective April 18, 2025 (SPL set 69582e0c-6569-490c-8c14-999f3750336f), via openFDA

Source: FDA drug label (Terazosin), Jubilant Cadista Pharmaceuticals Inc., effective May 5, 2026 (SPL set 43e92495-2cf2-46dd-a80c-f0c3c88c7b73), via openFDA; the full label on DailyMed

What does the verapamil label say about terazosin?

Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name terazosin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

21Terazosin generic labelers
43Verapamil generic labelers
TerazosinVerapamil
Labeled forEnlarged prostate (BPH), High blood pressureHigh blood pressure, Atrial fibrillation, Angina
Boxed warningNoNo
Pharmacy cost (NADAC)$0.106 per capsule 2 mg capsule$0.191 per tablet 180 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?