What the FDA labels say about taking them together
Digoxin and tamsulosin
Tamsulosin's FDA label of December 1, 2025 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name tamsulosin. The tamsulosin label: “Dosage adjustments are not necessary when a tamsulosin hydrochloride capsule is administered concomitantly with digoxin or theophylline.”
Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the tamsulosin FDA label on DailyMed (effective December 1, 2025, Synthon Pharmaceuticals, Inc.).
What does the digoxin label say about tamsulosin?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name tamsulosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
What does the tamsulosin label say about digoxin?
Tamsulosin label, drug interactionsDosage adjustments are not necessary when a tamsulosin hydrochloride capsule is administered concomitantly with digoxin or theophylline [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Tamsulosin hydrochloride), Synthon Pharmaceuticals, Inc., effective December 1, 2025 (SPL set 13a5032d-0be1-4001-916e-459f0b1a051d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Digoxin | Tamsulosin | |
|---|---|---|
| Labeled for | Heart failure, Atrial fibrillation | Enlarged prostate (BPH) |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.133 per tablet 125 mcg tablet | $0.05 per capsule 0.4 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once