What the FDA labels say about taking them together
Dobutamine and propranolol
Propranolol's FDA label of January 15, 2026 names dobutamine in its drug interactions section; the dobutamine labels PlainMeds reads (2) do not name propranolol. The propranolol label: “Propranolol may reduce sensitivity to dobutamine stress echocardiography in patients undergoing evaluation for myocardial ischemia.”
Check it at the source: the dobutamine FDA label on DailyMed (effective June 3, 2026, Hospira, Inc.); the propranolol FDA label on DailyMed (effective January 15, 2026, Mylan Pharmaceuticals Inc.).
What does the dobutamine label say about propranolol?
Dobutamine's label (effective June 3, 2026) and its 1 other brand-application label do not name propranolol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Dobutamine in Dextrose), Hospira, Inc., effective June 3, 2026 (SPL set 9943a961-3b50-4847-8a84-d8414ce38daa), via openFDA; the full label on DailyMed
What does the propranolol label say about dobutamine?
Propranolol label, drug interactionsIsoproterenol and Dobutamine Propranolol is a competitive inhibitor of beta-receptor agonists, and its effects can be reversed by administration of such agents, e.g., dobutamine or isoproterenol.
Inderal Xl label (ANI Pharmaceuticals, Inc., August 27, 2026), drug interactionsPropranolol may reduce sensitivity to dobutamine stress echocardiography in patients undergoing evaluation for myocardial ischemia.
Source: FDA drug label (Inderal Xl, NDA021438), ANI Pharmaceuticals, Inc., effective August 27, 2026 (SPL set ac196ff5-9215-402b-bc57-69aa87f8bade), via openFDA
Source: FDA drug label (Propranolol Hydrochloride), Mylan Pharmaceuticals Inc., effective January 15, 2026 (SPL set b94dcec7-7633-4a33-9cea-48161adeaf93), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dobutamine | Propranolol | |
|---|---|---|
| Labeled for | n/a | High blood pressure, Angina, Atrial fibrillation, Migraine |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0493 per tablet 20 mg tablet |
| Shortage now | In shortage | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once