Formoterol and Aclidinium Interaction
Drug interaction information between Formoterol and Aclidinium.
Formoterol and Aclidinium have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Formoterol and Aclidinium. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These drugs can increase the effects on your heart and blood vessels. This might cause your heart to beat too fast or raise your blood pressure.
FDA Label Information
May potentiate effect of formoterol fumarate on cardiovascular system. ( 7.6 ) 7.1 Adrenergic Drugs If additional adrenergic drugs are to be administered by any route, they should be used with caution because the sympathetic effects of formoterol, a component of DUAKLIR PRESSAIR, may be potentiated [see Warnings and Precautions (5.7) ] . 7.2 Xanthine Derivatives, Steroids Concomitant treatment with xanthine derivatives, or steroids may potentiate any hypokalemic effect of beta-adrenergic agonists such as formoterol, a component of DUAKLIR PRESSAIR.
Formoterol Also Interacts With
- Budesonide/Formoterol moderate
- Glycopyrrolate/Formoterol moderate
Frequently Asked Questions
What SPL severity band is on file for Formoterol + Aclidinium?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Formoterol has 3 labeled pairs on file vs Aclidinium's 1. In the moderate band specifically: Formoterol has 3 (also Budesonide/Formoterol, Glycopyrrolate/Formoterol); Aclidinium has 1.
What mechanism field is on file for Formoterol and Aclidinium?
These drugs can increase the effects on your heart and blood vessels. This might cause your heart to beat too fast or raise your blood pressure.
Formoterol's labeled portfolio outnumbers Aclidinium
SPL source-record counts only. This page's band is moderate · classes on file: Formoterol (Long-Acting Beta-2 Agonist (LABA)); Aclidinium (Long-Acting Muscarinic Antagonist (LAMA)).
0 major · 3 moderate · 0 minor · 3 total
- Other moderate peers for Formoterol
- Budesonide/Formoterol
- Glycopyrrolate/Formoterol
0 major · 1 moderate · 0 minor · 1 total
Aclidinium has no other moderate-band peer in this dataset besides Formoterol.
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.