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What the FDA labels say about taking them together

Exenatide and warfarin

Exenatide's FDA label of September 2, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name exenatide. The exenatide label: “… postmarketing reports for BYETTA of increased INR with concomitant use of warfarin, sometimes associated with bleeding.”

Check it at the source: the exenatide FDA label on DailyMed (effective September 2, 2025); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the exenatide label say about warfarin?

Exenatide label, drug interactions

Clinical Impact; In a drug interaction study, BYETTA did not have a significant effect on INR [see ]. There have been postmarketing reports for BYETTA of increased INR with concomitant use of warfarin, sometimes associated with bleeding [see ].

Source: FDA drug label (Byetta), AstraZeneca Pharmaceuticals LP, effective September 2, 2025 (SPL set 53d03c03-ebf7-418d-88a8-533eabd2ee4f), via openFDA; the full label on DailyMed

What does the warfarin label say about exenatide?

Warfarin's label (effective May 29, 2026) does not name exenatide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Exenatide generic labelers
19Warfarin generic labelers
ExenatideWarfarin
Labeled forType 2 diabetesBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$300.17 per mL 10 mcg dose pen injection$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?