What the FDA labels say about taking them together
Eravacycline and tetracycline
Eravacycline's FDA label of March 31, 2025 names tetracycline in its warnings and precautions section; the tetracycline label PlainMeds reads does not name eravacycline. The eravacycline label: “A decrease in fibula growth rate has been observed in premature infants given oral tetracycline in doses of 25 mg/kg every 6 hours.”
Check it at the source: the eravacycline FDA label on DailyMed (effective March 31, 2025, Tetraphase Pharmaceuticals, Inc.); the tetracycline FDA label on DailyMed (effective March 18, 2025, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.).
What does the eravacycline label say about tetracycline?
Eravacycline label, warnings and precautionsA decrease in fibula growth rate has been observed in premature infants given oral tetracycline in doses of 25 mg/kg every 6 hours.
Source: FDA drug label (Xerava), Tetraphase Pharmaceuticals, Inc., effective March 31, 2025 (SPL set a4b188d4-f467-470c-ad7b-25ffbdd8862a), via openFDA; the full label on DailyMed
What does the tetracycline label say about eravacycline?
Tetracycline's label (effective March 18, 2025) does not name eravacycline in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (tetracycline hydrochloride), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective March 18, 2025 (SPL set eaa5b1bd-0927-46e4-b941-32fcc492d258), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Eravacycline | Tetracycline | |
|---|---|---|
| Labeled for | n/a | Bacterial infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.247 per capsule 250 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once