What the FDA labels say about taking them together
Doxazosin and voriconazole
Doxazosin's FDA label (Cardura Xl) of May 15, 2023 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name doxazosin.
Check it at the source: the doxazosin FDA label on DailyMed (effective October 15, 2023, Viatris Specialty LLC); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the doxazosin label say about voriconazole?
Cardura Xl label (Viatris Specialty LLC, May 15, 2023), drug interactionsCaution should be exercised when concomitantly administering CARDURA XL with a strong CYP 3A4 inhibitor, such as atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole [see Clinical Pharmacology (12.3) ].
Cardura Xl label (Viatris Specialty LLC, May 15, 2023), warnings and precautionsCYP 3A4 Inhibitors Caution should be exercised when concomitantly administering CARDURA XL with a strong CYP 3A4 inhibitor, such as atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin, or voriconazole.
Source: FDA drug label (Cardura Xl, NDA021269), Viatris Specialty LLC, effective May 15, 2023 (SPL set 355bcdce-0481-48ba-8ebd-2009106aaf77), via openFDA
Source: FDA drug label (Cardura), Viatris Specialty LLC, effective October 15, 2023 (SPL set 5e1f5e49-2da1-43ab-9795-228a8bcc5a82), via openFDA; the full label on DailyMed
What does the voriconazole label say about doxazosin?
Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name doxazosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Doxazosin | Voriconazole | |
|---|---|---|
| Labeled for | Enlarged prostate (BPH), High blood pressure | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0752 per tablet 1 mg tablet | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once