What the FDA labels say about taking them together
Dicloxacillin and probenecid
Dicloxacillin's FDA label of December 27, 2023 names probenecid in its drug interactions section; the probenecid label PlainMeds reads does not name dicloxacillin. The dicloxacillin label: “Probenecid administered concomitantly with penicillins increases and prolongs serum penicillin levels.”
Check it at the source: the dicloxacillin FDA label on DailyMed (effective December 27, 2023, Aurobindo Pharma Limited); the probenecid FDA label on DailyMed (effective January 5, 2021, Lannett Company, Inc.).
What does the dicloxacillin label say about probenecid?
Dicloxacillin label, drug interactionsProbenecid administered concomitantly with penicillins increases and prolongs serum penicillin levels (see DOSAGE AND ADMINISTRATION ).
Source: FDA drug label (DICLOXACILLIN SODIUM), Aurobindo Pharma Limited, effective December 27, 2023 (SPL set 9074b5a6-850c-4144-9097-bb21073ee54d), via openFDA; the full label on DailyMed
What does the probenecid label say about dicloxacillin?
Probenecid's label (effective January 5, 2021) does not name dicloxacillin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Probenecid), Lannett Company, Inc., effective January 5, 2021 (SPL set ab497fd8-00c3-4364-b003-b39d21fbdf38), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dicloxacillin | Probenecid | |
|---|---|---|
| Labeled for | n/a | Gout |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.590 per capsule 250 mg capsule | $0.636 per tablet 500 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once