Digoxin · more major-labeled pairs than Dapagliflozin
SPL labels Dapagliflozin + Digoxin as minor; Dapagliflozin 13 / Digoxin 105 in that band.
Mechanism on file: These two drugs do not have a significant impact on how much of the other is present in your blood.
FDA SPL severity: Minor
Dapagliflozin + Digoxin · SPL mechanism field
These two drugs do not have a significant impact on how much of the other is present in your blood.
Minor band excerpt · Dapagliflozin with Digoxin
No dosing adjustments required for the following: Oral Antidiabetic Agents Metformin (1000 mg) 20 mg ↔ ↔ Pioglitazone (45 mg) 50 mg ↓7% [↓25%, ↑15%] ↔ Sitagliptin (100 mg) 20 mg ↔ ↔ Glimepiride (4 mg) 20 mg ↔ ↑13% [0%, ↑29%] Other Medications Hydrochlorothiazide (25 mg) 50 mg ↔ ↔ Bumetanide (1 mg) 10 mg once daily for 7 days ↑13% [↓2%, ↑31%] ↑13% [↓1%, ↑30%] Valsartan (320 mg) 20 mg ↓6% [↓24%, ↑16%] ↑5% [↓15%, ↑29%] Simvastatin (40 mg) 20 mg ↔ ↑19% Digoxin (0.25 mg) 20 mg loading dose then 10 mg once daily for 7 days ↔ ↔ Warfarin (25 mg) 20 mg loading dose then 10 mg once daily for 7 days...
Dapagliflozin · 13 minor + 13 total pairs
- Bumetanide minor
- Glimepiride minor
- Hydrochlorothiazide minor
- Lithium minor
Digoxin · 2 major-labeled pairs (vs Dapagliflozin's 0)
- Acarbose minor
- Albuterol minor
- Amiodarone minor
- Atorvastatin minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.