Itraconazole · more major-labeled pairs than Colchicine
SPL labels Colchicine + Itraconazole as major; Colchicine 4 / Itraconazole 19 in that band.
Mechanism on file: In people with liver or kidney issues, itraconazole prevents the body from removing colchicine, which can lead to dangerous side effects.
FDA SPL severity: Major
Colchicine + Itraconazole · SPL mechanism field
In people with liver or kidney issues, itraconazole prevents the body from removing colchicine, which can lead to dangerous side effects.
Major band excerpt · Colchicine with Itraconazole
Miscellaneous Drugs and Other Substances Colchicine Patients with renal or hepatic impairment: Contraindicated during and 2 weeks after itraconazole treatment.
Colchicine · 4 major + 28 total pairs
- Clarithromycin major
- Darunavir major
- Nirmatrelvir/Ritonavir major
- Atorvastatin moderate
Itraconazole · 19 major-labeled pairs (vs Colchicine's 4)
- Atorvastatin major
- Dofetilide major
- Dronedarone major
- Eplerenone major
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.