Carbamazepine · more major-labeled pairs than Clozapine
SPL labels Clozapine + Carbamazepine as minor; Clozapine 39 / Carbamazepine 110 in that band.
Mechanism on file: Carbamazepine speeds up the removal of clozapine from your body, which can make it less effective.
FDA SPL severity: Minor
Clozapine + Carbamazepine · SPL mechanism field
Carbamazepine speeds up the removal of clozapine from your body, which can make it less effective.
Minor band excerpt · Clozapine with Carbamazepine
In addition, carbamazepine causes, or would be expected to cause, decreased levels of the following drugs, for which monitoring of concentrations or dosage adjustment may be necessary: acetaminophen, albendazole, alprazolam, aprepitant, buprenorphone, bupropion, citalopram, clonazepam, clozapine, corticosteroids (e.g., prednisolone, dexamethasone), cyclosporine, dicumarol, dihydropyridine calcium channel blockers (e.g., felodipine), doxycycline, ethosuximide, everolimus, haloperidol, imatinib, itraconazole, lamotrigine, levothyroxine, methadone, methsuximide, mianserin, midazolam,...
Clozapine · 39 minor + 42 total pairs
- Amiodarone minor
- Bupropion minor
- Chlorpromazine minor
- Cimetidine minor
Carbamazepine · 3 major-labeled pairs (vs Clozapine's 0)
- Acetaminophen minor
- Acetaminophen/Oxycodone minor
- Albendazole minor
- Alprazolam minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.