What the FDA labels say about taking them together
Ciprofloxacin and lanthanum
Ciprofloxacin's FDA label of March 2, 2026 names lanthanum in its drug interactions section, and lanthanum's label names ciprofloxacin too. The lanthanum label: “The bioavailability of oral ciprofloxacin was decreased by approximately 50% when taken with FOSRENOL in a single-dose study in healthy volunteers.”
Check it at the source: the ciprofloxacin FDA label on DailyMed (effective March 2, 2026, Bayer HealthCare Pharmaceuticals Inc.); the lanthanum FDA label on DailyMed (effective December 31, 2024, Takeda Pharmaceuticals America, Inc.).
What does the ciprofloxacin label say about lanthanum?
Ciprofloxacin label, drug interactionsAntacids, Sucralfate, Multivitamins and Other Products Containing Multivalent Cations (magnesium/aluminum antacids; polymeric phosphate binders (for example, sevelamer, lanthanum carbonate); sucralfate; Videx ® (didanosine) chewable/buffered tablets or pediatric powder; other highly buffered drugs; or products containing calcium, iron, or zinc and dairy products); CIPRO should be taken at least two hours before or six hours after Multivalent cation-containing products administration [see Dosage and Administration ()].; Decrease CIPRO absorption, resulting in lower serum and urine levels
Source: FDA drug label (Cipro), Bayer HealthCare Pharmaceuticals Inc., effective March 2, 2026 (SPL set 888dc7f9-ad9c-4c00-8d50-8ddfd9bd27c0), via openFDA; the full label on DailyMed
What does the lanthanum label say about ciprofloxacin?
Lanthanum label, drug interactionsThe bioavailability of oral ciprofloxacin was decreased by approximately 50% when taken with FOSRENOL in a single-dose study in healthy volunteers.
Source: FDA drug label (Fosrenol), Takeda Pharmaceuticals America, Inc., effective December 31, 2024 (SPL set f10776b2-2c25-4343-aabe-68f302e5cb54), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ciprofloxacin | Lanthanum | |
|---|---|---|
| Labeled for | Diarrhea, Urinary tract infections, Bacterial infections | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.123 per tablet 500 mg tablet | $3.15 per tablet 1,000 mg tablet chw |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once