What the FDA labels say about taking them together
Chlorpromazine and propranolol
Propranolol's FDA label of January 15, 2026 names chlorpromazine in its drug interactions section; the chlorpromazine label PlainMeds reads does not name propranolol. The propranolol label: “Co-administration of chlorpromazine with propranolol resulted in a 70% increase in propranolol plasma level.”
Check it at the source: the chlorpromazine FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC); the propranolol FDA label on DailyMed (effective January 15, 2026, Mylan Pharmaceuticals Inc.).
What does the chlorpromazine label say about propranolol?
Chlorpromazine's label (effective May 12, 2026) does not name propranolol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CHLORPROMAZINE HYDROCHLORIDE), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set aa086a21-de85-4b03-af58-49b70acf8cf0), via openFDA; the full label on DailyMed
What does the propranolol label say about chlorpromazine?
Propranolol label, drug interactionsCo-administration of chlorpromazine with propranolol resulted in a 70% increase in propranolol plasma level.
Source: FDA drug label (Propranolol Hydrochloride), Mylan Pharmaceuticals Inc., effective January 15, 2026 (SPL set b94dcec7-7633-4a33-9cea-48161adeaf93), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Chlorpromazine | Propranolol | |
|---|---|---|
| Labeled for | Schizophrenia, Nausea and vomiting | High blood pressure, Angina, Atrial fibrillation, Migraine |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.552 per tablet 100 mg tablet | $0.0493 per tablet 20 mg tablet |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once