Amphotericin B · more major-labeled pairs than Dexamethasone
SPL labels Dexamethasone + Amphotericin B as minor; Dexamethasone 18 / Amphotericin B 9 in that band.
Mechanism on file: Both drugs can cause your body to lose too much potassium. Having very low potassium levels can lead to serious heart problems.
FDA SPL severity: Minor
Dexamethasone + Amphotericin B · SPL mechanism field
Both drugs can cause your body to lose too much potassium. Having very low potassium levels can lead to serious heart problems.
Minor band excerpt · Dexamethasone with Amphotericin B
Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. In addition, there have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure.
Dexamethasone · 21 SPL pairs (broader portfolio than Amphotericin B)
- Albendazole minor
- Aprepitant minor
- Carbamazepine minor
- Caspofungin minor
Amphotericin B · 1 major-labeled pairs (vs Dexamethasone's 0)
- Anidulafungin minor
- Dronabinol minor
- Fluconazole minor
- Fludrocortisone minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.