Desipramine · larger labeled portfolio than Atomoxetine
SPL labels Atomoxetine + Desipramine as minor; Atomoxetine 14 / Desipramine 18 in that band.
Mechanism on file: Atomoxetine does not change how the body processes desipramine, even though both drugs use the same liver enzyme.
FDA SPL severity: Minor
Atomoxetine + Desipramine · SPL mechanism field
Atomoxetine does not change how the body processes desipramine, even though both drugs use the same liver enzyme.
Minor band excerpt · Atomoxetine with Desipramine
CYP2D6 Substrate (e.g., Desipramine) — Coadministration of atomoxetine (40 or 60 mg BID for 13 days) with desipramine, a model compound for CYP2D6 metabolized drugs (single dose of 50 mg), did not alter the pharmacokinetics of desipramine.
Atomoxetine · 14 minor + 15 total pairs
- Celecoxib minor
- Desvenlafaxine minor
- Diazepam minor
- Dobutamine minor
Desipramine · 18 SPL pairs (broader portfolio than Atomoxetine)
- Bupropion minor
- Darunavir minor
- Desvenlafaxine minor
- Dopamine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.