What the FDA labels say about taking them together
Amiodarone and cobicistat
Cobicistat's FDA label of February 10, 2026 names amiodarone in its drug interactions section; the amiodarone labels PlainMeds reads (2) do not name cobicistat. The cobicistat label: “Clinical monitoring is recommended upon coadministration with antiarrhythmics.”
Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the cobicistat FDA label on DailyMed (effective February 10, 2026, Gilead Sciences, Inc.).
What does the amiodarone label say about cobicistat?
Amiodarone's label (effective December 9, 2025) and its 1 other brand-application label do not name cobicistat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed
What does the cobicistat label say about amiodarone?
Cobicistat label, drug interactionsConcomitant Drug Class/Drug Name: Other antiarrhythmics: e.g., amiodarone disopyramide flecainide mexiletine propafenone quinidine; Potential Effect ↑ = Increase, ↓ = Decrease, ↔ = No change: ↑ antiarrhythmics; Clinical Comment: Clinical monitoring is recommended upon coadministration with antiarrhythmics.
Source: FDA drug label (Tybost), Gilead Sciences, Inc., effective February 10, 2026 (SPL set 3784c35c-e87f-410c-900b-8fd6313c6010), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amiodarone | Cobicistat | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.122 per tablet 200 mg tablet | n/a |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once