What the FDA labels say about taking them together
Amikacin and vancomycin
Amikacin's FDA label of December 10, 2025 names vancomycin in its boxed warning section; the vancomycin labels PlainMeds reads (4) do not name amikacin.
Check it at the source: the amikacin FDA label on DailyMed (effective December 10, 2025, Qilu Pharmaceutical Co., Ltd.); the vancomycin FDA label on DailyMed (effective June 7, 2024, Mylan Institutional LLC).
What does the amikacin label say about vancomycin?
Amikacin label, boxed warningConcurrent and/or sequential systemic, oral or topical use of other neurotoxic or nephrotoxic products, particularly bacitracin, cisplatin, amphotericin B, cephaloridine, paromomycin, viomycin, polymyxin B, colistin, vancomycin, or other aminoglycosides should be avoided.
Source: FDA drug label (Amikacin Sulfate), Qilu Pharmaceutical Co., Ltd., effective December 10, 2025 (SPL set 20fa61ef-11e2-4d01-82ea-b5412cefaead), via openFDA; the full label on DailyMed
What does the vancomycin label say about amikacin?
Vancomycin's label (effective June 7, 2024) and its 3 other brand-application labels do not name amikacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Vancomycin Hydrochloride), Mylan Institutional LLC, effective June 7, 2024 (SPL set caf22ccb-df75-45ea-a1d0-ccb2d37272fb), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amikacin | Vancomycin | |
|---|---|---|
| Labeled for | Bacterial infections | Bacterial infections, Diarrhea |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.33 per mL 500 mg/2 mL vial | $1.33 per capsule 125 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once