What the FDA labels say about taking them together
Amikacin and furosemide
Amikacin's FDA label of December 10, 2025 names furosemide in its boxed warning section; the furosemide labels PlainMeds reads (4) do not name amikacin. The amikacin label: “Avoid concomitant use of ARIKAYCE with ethacrynic acid, furosemide, urea, or intravenous mannitol.”
Check it at the source: the amikacin FDA label on DailyMed (effective December 10, 2025, Qilu Pharmaceutical Co., Ltd.); the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC).
What does the amikacin label say about furosemide?
Amikacin label, boxed warningThe concurrent use of amikacin with potent diuretics (ethacrynic acid, or furosemide) should be avoided since diuretics by themselves may cause ototoxicity.
Arikayce label (Insmed Incorporated, August 4, 2026), drug interactionsAvoid concomitant use of ARIKAYCE with ethacrynic acid, furosemide, urea, or intravenous mannitol.
Source: FDA drug label (Arikayce, NDA207356), Insmed Incorporated, effective August 4, 2026 (SPL set 499ab990-2b21-474f-aaba-d86388965f40), via openFDA
Source: FDA drug label (Amikacin Sulfate), Qilu Pharmaceutical Co., Ltd., effective December 10, 2025 (SPL set 20fa61ef-11e2-4d01-82ea-b5412cefaead), via openFDA; the full label on DailyMed
What does the furosemide label say about amikacin?
Furosemide's label (effective September 30, 2025) and its 3 other brand-application labels do not name amikacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amikacin | Furosemide | |
|---|---|---|
| Labeled for | Bacterial infections | Heart failure, High blood pressure, Edema (fluid retention) |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.33 per mL 500 mg/2 mL vial | $0.490 per mL 20 mg/2 mL vial |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once