Acetaminophen/Oxycodone and Acetaminophen · Minor SPL band

SPL labels Acetaminophen/Oxycodone + Acetaminophen as minor; Acetaminophen/Oxycodone 21 / Acetaminophen 21 in that band.

Mechanism on file: Taking both of these medicines at the same time means you are getting the same active ingredient from two different sources, which can lead to a dangerous buildup in your liver.

FDA SPL severity: Minor

Acetaminophen/Oxycodone

Full Acetaminophen/Oxycodone label record

Opioid Analgesic Combination

Acetaminophen

Full Acetaminophen label record

Analgesic / Antipyretic

Acetaminophen/Oxycodone + Acetaminophen · SPL mechanism field

Taking both of these medicines at the same time means you are getting the same active ingredient from two different sources, which can lead to a dangerous buildup in your liver.

Minor band excerpt · Acetaminophen/Oxycodone with Acetaminophen

Alcohol, ethyl Hepatotoxicity has occurred in chronic alcoholics following various dose levels (moderate to excessive) of acetaminophen. Oral Contraceptives Increase in glucuronidation resulting in increased plasma clearance and a decreased half-life of acetaminophen. Charcoal (activated) Reduces acetaminophen absorption when administered as soon as possible after overdose.

Acetaminophen · 21 minor + 23 total pairs

View all Acetaminophen interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.