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What the FDA labels say about taking them together

Abiraterone and thioridazine

Abiraterone's FDA label of March 28, 2025 names thioridazine in its drug interactions section; the thioridazine label PlainMeds reads does not name abiraterone. The abiraterone label: “Avoid co-administration of abiraterone acetate with substrates of CYP2D6 with a narrow therapeutic index (e.g., thioridazine).”

Check it at the source: the abiraterone FDA label on DailyMed (effective March 28, 2025, Janssen Biotech, Inc.); the thioridazine FDA label on DailyMed (effective November 11, 2025, Mylan Institutional Inc.).

What does the abiraterone label say about thioridazine?

Abiraterone label, drug interactions

Avoid co-administration of abiraterone acetate with substrates of CYP2D6 with a narrow therapeutic index (e.g., thioridazine).

Source: FDA drug label (Zytiga), Janssen Biotech, Inc., effective March 28, 2025 (SPL set 4e338e89-3cf2-48eb-b6e2-a06c608c6513), via openFDA; the full label on DailyMed

What does the thioridazine label say about abiraterone?

Thioridazine's label (effective November 11, 2025) does not name abiraterone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Thioridazine Hydrochloride), Mylan Institutional Inc., effective November 11, 2025 (SPL set 52fea941-0b47-41c1-b00d-f88150e8ab93), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

23Abiraterone generic labelers
5Thioridazine generic labelers
AbirateroneThioridazine
Labeled forProstate cancern/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.774 per tablet 250 mg tablet$0.571 per tablet 25 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?