Prescription medicine
Zolmitriptan Brand names: Zomig
Zolmitriptan (Zomig) is a prescription medicine with an FDA approval on record since 1997. FDA's NDC Directory lists it from 20 generic labelers, and pharmacies paid $1.02 per zolmitriptan 2.5 mg tablet in the October 7, 2026 NADAC survey.
- Generic listed
Check it at the source: the zolmitriptan FDA label on DailyMed (effective January 29, 2026, Glenmark Pharmaceuticals Inc.,USA); the NDA 20768 record on Drugs@FDA; every zolmitriptan label on DailyMed.
Highlights of the record
FDA label of January 29, 2026; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026
Used for
From the label: indications and usageZolmitriptan tablets are indicated for the acute treatment of migraine with or without aura in adults.
Forms and strengths
- 2.5 mg
- 5 mg
Film-coated tablet; orally disintegrating tablet; tablet; spray; spray (metered).
On the market
- Earliest approval on file
- November 25, 1997 Zomig, Ipr; Drugs@FDA’s file, where older or withdrawn approvals can be missing
- Generic approvals
- 23 first May 14, 2013; 14 with a marketed status in Drugs@FDA
- Labelers listed (NDC)
- 21 of which 20 under generic applications, 0 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- $1.02 per tablet Zolmitriptan 2.5 mg tablet
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 7,155 through July 30, 2026
What is zolmitriptan used for?
From the label: indications and usageZolmitriptan tablets are indicated for the acute treatment of migraine with or without aura in adults. Limitations of Use
Only use zolmitriptan tablets if a clear diagnosis of migraine has been established. If a patient has no response to zolmitriptan tablets treatment for the first migraine attack, reconsider the diagnosis of migraine before zolmitriptan tablets are administered to treat any subsequent attacks.
Zolmitriptan tablets are not indicated for the prevention of migraine attacks.
Safety and effectiveness of zolmitriptan tablets have not been established for cluster headache. […]
Conditions named in the indications of zolmitriptan's FDA labels, with every medicine labeled for each:
FDA pharmacologic class: Serotonin-1b and Serotonin-1d Receptor Agonist.
Source: FDA drug label (Zolmitriptan), Glenmark Pharmaceuticals Inc.,USA, effective January 29, 2026 (SPL set 333caafc-2e63-49f8-a0c6-534e528d228d), via openFDA; the full label on DailyMed
Is there a generic for zolmitriptan (Zomig)?
The FDA approved the first generic zolmitriptan on May 14, 2013. 23 generic applications are approved; 14 of them carry a current (not discontinued) marketing status in Drugs@FDA; that status is not evidence that the generic is on sale.
FDA's NDC Directory lists zolmitriptan from 20 labelers under a generic (ANDA) application. A listing means the company has registered the product for sale; it does not show that every pharmacy stocks it.
- 1997 earliest approval on file
- 2013 first generic approved
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do pharmacies pay for zolmitriptan (Zomig)?
In CMS's NADAC survey of October 7, 2026, pharmacies paid $1.02 per Zolmitriptan 2.5 mg tablet, down 20% from $1.29 on October 8, 2025. Prices per unit in the table differ many-fold by strength, form and brand, so compare like with like. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.
- Zolmitriptan 2.5 mg tablet (generic)
| Strength and form | Brand or generic | Pharmacy cost | 30 tablets, or one pen or vial | 12-month change |
|---|---|---|---|---|
| Zolmitriptan 2.5 mg ODT | Generic | $2.07 per unit | n/a | -14% |
| Zolmitriptan 2.5 mg tablet | Generic | $1.02 per tablet | $30.68 | -20% |
| Zolmitriptan 5 mg nasal spray | Generic | $44.04 per unit many times the lowest per-tablet cost; NADAC records the price, not why | n/a | -2% |
| Zolmitriptan 5 mg ODT | Generic | $3.25 per unit | n/a | -2% |
| Zolmitriptan 5 mg tablet | Generic | $1.35 per tablet | $40.60 | +0.5% |
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What does the zolmitriptan label say about other medicines?
The zolmitriptan label names 3 other medicines in its interaction, contraindication or warning sections. The labels of 1 other medicine name zolmitriptan. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
| Medicine named | Section | What the label says |
|---|---|---|
| Cimetidine | drug interactions | Following administration of cimetidine, the half-life and blood levels of zolmitriptan and its active N-desmethyl metabolite were approximately doubled [ see Clinical Pharmacology ( 12.3 ) ]. |
| Dihydroergotamine | contraindications | Recent use (i.e., within 24 hours) of another 5-HT 1 agonist, ergotamine-containing medication, or ergot-type medication (such as dihydroergotamine or methysergide) [see Drug Interactions ( 7.1 , 7.3 ) ] |
| Ergotamine | warnings and precautions | Overuse of acute migraine drugs (e.g., ergotamine, triptans, opioids, or a combination of drugs for 10 or more days per month) may lead to exacerbation of headache (medication overuse headache). |
Other labels that name zolmitriptan
Source: FDA drug label (Zolmitriptan), Glenmark Pharmaceuticals Inc.,USA, effective January 29, 2026 (SPL set 333caafc-2e63-49f8-a0c6-534e528d228d), via openFDA; the full label on DailyMed
What do FAERS reports show for zolmitriptan?
The FDA Adverse Event Reporting System holds 7,155 reports that list zolmitriptan among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 169 are coded as a death and 1,687 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What else is labeled for the same conditions as zolmitriptan?
12 other medicines are given the same way (oral) and in the same FDA class as zolmitriptan or labeled mainly for the same use (migraine), the same class first. Migraine lists all 27 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.
| Medicine | Shared indication | Generic labelers (oral) | Pharmacy cost | Shortage |
|---|---|---|---|---|
| Sumatriptan | Migraine | 22 labelers | $0.302 per tablet 50 mg tablet | No current entry |
| Rizatriptan | Migraine | 25 labelers | $0.335 per tablet 10 mg tablet | No current entry |
| Eletriptan | Migraine | 10 labelers | $1.75 per tablet 40 mg tablet | No current entry |
| Naratriptan | Migraine | 4 labelers | $1.08 per tablet 2.5 mg tablet | No current entry |
| Almotriptan | Migraine | 3 labelers | $16.86 per tablet 12.5 mg tablet | No current entry |
| Naproxen and sumatriptan | Migraine | 3 labelers | $10.46 per unit 85-500 mg | No current entry |
| Frovatriptan | Migraine | 4 labelers | $2.72 per tablet 2.5 mg tablet | A presentation being discontinued |
| Meloxicam and rizatriptan | Migraine | none listed | $122.64 per tablet 20-10 mg tablet | No current entry |
Every medicine labeled for the same conditions as zolmitriptan
Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)
How does zolmitriptan compare with medicines for the same use?
4 side-by-side pages set zolmitriptan beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.
What next?
- Alternatives to zolmitriptan
- 12 medicines for the same use
- Other triptans
- the pharmacologic class, with prices and generics
- Zolmitriptan side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other