FDA pharmacologic class
Triptans
7 medicines are in FDA's class of serotonin-1b and serotonin-1d receptor agonists (triptans): sumatriptan (Imitrex), rizatriptan (Maxalt), zolmitriptan (Zomig), eletriptan (Relpax), naratriptan, almotriptan and frovatriptan; 2 combination products also contain one. 8 of the 9 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is sumatriptan succ 50 mg tablet at $0.302 per tablet (NADAC).
Which medicines are triptans?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Sumatriptan | Imitrex, Tosymra, Zembrace | 39 labelers | $0.302 per tablet 50 mg tablet | No | No current entry | 6 |
| Rizatriptan | Rizafilm, Maxalt, Maxalt-Mlt | 22 labelers | $0.335 per tablet 10 mg tablet | No | No current entry | 9 |
| Zolmitriptan | Zomig | 20 labelers | $1.02 per tablet 2.5 mg tablet | No | No current entry | 0 |
| Eletriptan | Relpax | 10 labelers | $1.75 per tablet 40 mg tablet | No | No current entry | 1 |
| Naratriptan | none listed | 4 labelers | $1.08 per tablet 2.5 mg tablet | No | No current entry | 0 |
| Almotriptan | none listed | 3 labelers | $16.86 per tablet 12.5 mg tablet | No | No current entry | 0 |
| Naproxen and sumatriptan | Treximet | 3 labelers | $10.46 per unit 85-500 mg | Yes | No current entry | 0 |
| Frovatriptan | none listed | 4 labelers | $2.72 per tablet 2.5 mg tablet | No | A presentation being discontinued | 2 |
| Meloxicam and rizatriptan | Symbravo | none listed | $122.64 per tablet 20-10 mg tablet | Yes | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price