amikacin vs tedizolid
Side-by-side comparison of amikacin and tedizolid Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Amikacin is an antibiotic medicine. It fights serious infections caused by certain types of bacteria.
Tedizolid (Sivextro) is an antibiotic medicine. It fights certain bacteria that cause skin infections.
Amikacin treats serious infections caused by bacteria. This includes infections in the blood, lungs, bones, joints, brain, skin, and abdomen. It can also treat burns, post-surgery infections, and complicated urinary tract infections.
Tedizolid treats acute bacterial skin infections. This includes infections like cellulitis and major skin abscesses. It works against bacteria such as Staphylococcus aureus (including MRSA), Streptococcus pyogenes, and others. It is for adults and children at least 26 weeks gestational age and weighing at least 1 kg.
Amikacin belongs to a class of drugs called aminoglycosides. It works by stopping the growth of bacteria. This helps your body fight off the infection.
Tedizolid belongs to a class of drugs called oxazolidinones. It stops bacteria from growing by blocking their ability to make proteins. This helps your body fight off the infection.
No common side effects listed.
- • Nausea
- • Headache
- • Diarrhea
- • Vomiting
- • Dizziness
- Off Label Use 1,908
- Drug Ineffective 1,673
- Cough 1,620
- Dyspnoea 1,556
- Hospitalisation 1,360
- Off Label Use 109
- Product Use In Unapproved Indication 88
- Thrombocytopenia 60
- Anaemia 45
- Nausea 43
Amikacin can potentially cause hearing loss and kidney damage. Tell your doctor if you have kidney problems or are taking other medicines that can affect your hearing or kidneys. Your doctor should closely monitor you for hearing and kidney problems during treatment. This drug can also cause muscle weakness or breathing problems, especially if you are also taking anesthesia or certain muscle relaxants.
If you have a low white blood cell count (neutropenia), talk to your doctor. Tedizolid may not work as well. Diarrhea can happen while taking tedizolid or even months after. Tell your doctor right away if you get diarrhea.
Tell your doctor if you are pregnant or breastfeeding. Amikacin may harm your unborn baby. It is not known if amikacin passes into breast milk.
Tedizolid may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if tedizolid passes into breast milk, so talk to your doctor about breastfeeding.
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How to Read This amikacin vs tedizolid Comparison
amikacin is classified in the Aminoglycoside Antibiotic drug class, while tedizolid sits within the Oxazolidinone Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amikacin has 8,117 submissions while tedizolid has 345. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between amikacin and tedizolid — always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.