MID-VOLUME · FEMALE-LED
tretinoin Side Effects
tretinoin (also sold as Retin-A) sits MID-VOLUME #347 of 524 by FAERS report count. Lead signal: FEMALE-LED - 76% of sex-coded reports are female (5,040 F / 1,561 M). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 7,629
- FAERS reports
FDA Adverse Event Reporting System extract for tretinoin. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-MID. How figures are compiled.
tretinoin reporting skew - 76% of sex-coded reports are female (5,040 F / 1,561 M). Volume band MID-VOLUME #347 of 524 by FAERS report count; caseload WATCHLIST.
Mid-book FAERS page for tretinoin (Retin-A) (7,629 reports). Signature FEMALE-LED. Dominant age band on file: 18-44. Educational reference only.
Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
PAIN leads 536 of 7,629 reports
FEMALE-LED reporters · age peak 18-44
Female-led reporters (76% of sex-coded rows)
Age peak 18-44 (2,071 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (804 reports, 10.5%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| MATERNAL EXPOSURE DURING PREGNANCY | 212 |
| PNEUMONIA | 147 |
| CONTRAINDICATED PRODUCT ADMINISTERED | 144 |
| TASTE DISORDER | 144 |
| CONDITION AGGRAVATED | 143 |
| VOMITING | 143 |
| EPILEPSY | 139 |
| SYNOVITIS | 139 |
| TREATMENT FAILURE | 135 |
| PRODUCT QUALITY ISSUE | 134 |
| RHEUMATOID ARTHRITIS | 134 |
| ABDOMINAL PAIN UPPER | 131 |
| WEIGHT INCREASED | 131 |
| PAIN | 130 |
| PSORIATIC ARTHROPATHY | 129 |
Reactions in Hospitalization Reports
Hospitalization mid-share (1,549, 20.3%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| PAIN | 198 |
| VOMITING | 195 |
| NAUSEA | 174 |
| DIARRHOEA | 173 |
| PNEUMONIA | 150 |
| ARTHRALGIA | 144 |
| DEPRESSION | 138 |
| HEADACHE | 138 |
| DYSPNOEA | 132 |
| FATIGUE | 132 |
| RASH | 132 |
| DIZZINESS | 131 |
| PYREXIA | 130 |
| ASTHENIA | 128 |
| WEIGHT INCREASED | 124 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 122 |
| ABDOMINAL PAIN UPPER | 120 |
How to read tretinoin FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-MID)
FAERS holds 7,629 voluntary reports linked to tretinoin (Retin-A), 2004-2025. Death is listed on 804 (10.5%). Hospitalization appears on 1,549 (20.3%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-MID as signal-detection rates next to 76% of sex-coded reports are female (5,040 F / 1,561 M).
Read with tretinoin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 7,575 FAERS cases (Δ 54 lighter vs tretinoin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 7,480 FAERS cases (Δ 149 lighter vs tretinoin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 7,801 FAERS cases (Δ 172 heavier vs tretinoin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 7,819 FAERS cases (Δ 190 heavier vs tretinoin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.6 pp vs tretinoin's DEATH-HEAVY): CASELOAD · HOSP-MID.
tretinoin stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.