LOW-VOLUME · HOSP-MID

lisdexamfetamine Side Effects

lisdexamfetamine (also sold as Vyvanse) is a LOW-VOLUME FAERS extract #382 of 524 by FAERS report count. Still opens on HOSP-MID: 29.9% mention hospitalization (1,746 reports).

Data updated 2026-05-15

5,840
FAERS reports

Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.

lisdexamfetamine: 29.9% mention hospitalization (1,746 reports). Death stamp DEATH-MARKED; volume band LOW-VOLUME #382 of 524 by FAERS report count.

Thinner FAERS extract for lisdexamfetamine (Vyvanse) (5,840 reports #382 of 524 by FAERS report count). 29.9% mention hospitalization (1,746 reports). Sparse books still carry named reaction rows when present; not medical advice.

Counts from the openFDA FAERS extract (2007–2025). Stamps WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.

INTENTIONAL OVERDOSE leads 1,068 of 5,840 reports

INTENTIONAL OVERDOSE
1,068
INTENTIONAL SELF-INJURY
1,009
PRODUCT AVAILABILITY ISSUE
487
FATIGUE
402
HEADACHE
377
ANXIETY
357
INABILITY TO AFFORD MEDICATION
348
PRODUCT SUBSTITUTION ISSUE
344
DEPRESSION
303
CONDITION AGGRAVATED
268
INSOMNIA
248
INSURANCE ISSUE
230
SUICIDAL IDEATION
224
SOMNOLENCE
221
NAUSEA
217
FEELING ABNORMAL
216
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION
195

Who reports · age peak 18-44 (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 2,887 (61%)
Male 1,795 (38%)
Unknown 29

Age peak 18-44 (1,589 reports)

0-17 1,250 (37%)
18-44 1,589 (47%)
45-64 505 (15%)
65-74 41 (1%)
75+ 3 (0%)

FAERS filings rising toward 2025

2007 2025

Reactions in Death Reports

Death appears on 208 reports (3.6% - MARKED). Reactions below co-occur in those rows only.

Reaction Reports
COMPLETED SUICIDE 95
TOXICITY TO VARIOUS AGENTS 55
CARDIO-RESPIRATORY ARREST 38
DEATH 29
CARDIAC ARREST 23
RESPIRATORY ARREST 19
HYPOTENSION 13
COMA 12
SUSPECTED SUICIDE 12
DEPRESSED LEVEL OF CONSCIOUSNESS 10
METABOLIC ACIDOSIS 9
RESPIRATORY DEPRESSION 9
ANION GAP 7
CIRCULATORY COLLAPSE 6
SEIZURE 6
ADRENERGIC SYNDROME 5
HYPERTHERMIA 5
AGGRESSION 4
AGITATION 4
BLOOD CREATINE PHOSPHOKINASE INCREASED 4

Reactions in Hospitalization Reports

Hospitalization mid-share (1,746, 29.9%). Co-reported reactions:

Reaction Reports
INTENTIONAL OVERDOSE 895
INTENTIONAL SELF-INJURY 830
DRUG INTERACTION 105
TOXICITY TO VARIOUS AGENTS 95
SUICIDE ATTEMPT 77
AGITATION 59
OVERDOSE 54
SEROTONIN SYNDROME 48
TACHYCARDIA 47
VOMITING 46
NAUSEA 45
HYPOTENSION 43
ANXIETY 42
CARDIOGENIC SHOCK 41
HEADACHE 41
HYPERHIDROSIS 39
SUICIDAL IDEATION 37
DEPRESSION 33
How to read lisdexamfetamine FAERS figures (WATCHLIST · DEATH-MARKED · HOSP-MID)

FAERS holds 5,840 voluntary reports linked to lisdexamfetamine (Vyvanse), 2007-2025. Death is listed on 208 (3.6%). Hospitalization appears on 1,746 (29.9%). Top co-reported indication: Product Used For Unknown Indication.

Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.

Read with lisdexamfetamine

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.