HIGH-VOLUME · HOSP-HEAVY
simvastatin Side Effects
simvastatin (also sold as Zocor) is HIGH-VOLUME in this FAERS book #20 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 38.6% mention hospitalization (94,740 reports).
Data updated 2026-05-15
- 245,754
- FAERS reports
FAERS voluntary reports, 2002 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
simvastatin: 38.6% mention hospitalization (94,740 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #20 of 524 by FAERS report count.
High-report extract for simvastatin (Zocor): 245,754 FAERS rows (2002-2025). Top named reactions: FATIGUE, NAUSEA, DYSPNOEA. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2002–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 13,574 of 245,754 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (55,999 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (21,913 reports, 8.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 6,325 |
| SEPSIS | 1,509 |
| DYSPNOEA | 1,384 |
| PNEUMONIA | 1,384 |
| RENAL FAILURE | 1,320 |
| NAUSEA | 1,138 |
| FALL | 1,106 |
| MYOCARDIAL INFARCTION | 1,052 |
| ASTHENIA | 1,039 |
| VOMITING | 1,030 |
| ACUTE KIDNEY INJURY | 1,017 |
| DIARRHOEA | 997 |
| CARDIAC ARREST | 995 |
| COMPLETED SUICIDE | 901 |
| FATIGUE | 895 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 867 |
| RESPIRATORY FAILURE | 854 |
| ABDOMINAL PAIN | 848 |
| ANAEMIA | 813 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (94,740, 38.6% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DYSPNOEA | 6,628 |
| FALL | 6,061 |
| NAUSEA | 5,342 |
| DIARRHOEA | 4,933 |
| PNEUMONIA | 4,868 |
| ASTHENIA | 4,556 |
| FATIGUE | 4,543 |
| VOMITING | 4,525 |
| DIZZINESS | 4,469 |
| DRUG INTERACTION | 4,237 |
| RHABDOMYOLYSIS | 4,086 |
| ACUTE KIDNEY INJURY | 4,048 |
| ANAEMIA | 3,973 |
| MYOCARDIAL INFARCTION | 3,680 |
| HYPOTENSION | 3,599 |
| PAIN | 3,548 |
| MALAISE | 3,409 |
| PYREXIA | 3,296 |
| CHEST PAIN | 3,187 |
| DEHYDRATION | 3,078 |
How to read simvastatin FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 245,754 voluntary reports linked to simvastatin (Zocor), 2002-2025. Death is listed on 21,913 (8.9%). Hospitalization appears on 94,740 (38.6%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with simvastatin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 246,252 FAERS cases (Δ 498 heavier vs simvastatin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 241,433 FAERS cases (Δ 4,321 lighter vs simvastatin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 240,800 FAERS cases (Δ 4,954 lighter vs simvastatin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 240,204 FAERS cases (Δ 5,550 lighter vs simvastatin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.2 pp vs simvastatin's DEATH-HEAVY): CASELOAD · HOSP-MID.
simvastatin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.