MID-VOLUME · HOSP-HEAVY

senna Side Effects

senna (also sold as Senokot) sits MID-VOLUME #236 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 51.2% mention hospitalization (10,339 reports). Demographics and serious-outcome tables follow.

Data updated 2026-05-15

20,197
FAERS reports

FDA Adverse Event Reporting System extract for senna. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.

senna: 51.2% mention hospitalization (10,339 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #236 of 524 by FAERS report count.

Mid-book FAERS page for senna (Senokot) (20,197 reports). Signature HOSP-HEAVY. Dominant age band on file: 45-64. Educational reference only.

Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.

NAUSEA leads 1,390 of 20,197 reports

NAUSEA
1,390
FATIGUE
1,358
CONSTIPATION
1,157
DYSPNOEA
1,093
DIARRHOEA
1,064
DEATH
1,052
VOMITING
984
PNEUMONIA
945
FALL
885
PYREXIA
852
HEADACHE
832
PAIN
831
ASTHENIA
767
DIZZINESS
708
MALAISE
660
RASH
599
ABDOMINAL PAIN
590
ACUTE KIDNEY INJURY
580
CONFUSIONAL STATE
576

Who reports · age peak 45-64 (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 10,288 (54%)
Male 8,716 (46%)
Unknown 38

Age peak 45-64 (4,634 reports)

0-17 472 (3%)
18-44 1,676 (11%)
45-64 4,634 (31%)
65-74 3,587 (24%)
75+ 4,489 (30%)

FAERS filings rising toward 2025

2004 2025

Reactions in Death Reports

Death-mentioned subset is HEAVY here (3,098 reports, 15.3%). Top co-reported reactions in that subset - voluntary, not causal.

Reaction Reports
DEATH 1,046
PNEUMONIA 315
DYSPNOEA 239
SEPSIS 188
PYREXIA 170
FATIGUE 165
VOMITING 159
RESPIRATORY FAILURE 149
DISEASE PROGRESSION 148
NAUSEA 148
ACUTE KIDNEY INJURY 144
ASTHENIA 140
FALL 132
PAIN 123
CONSTIPATION 122
DIARRHOEA 122
MALIGNANT NEOPLASM PROGRESSION 122
CARDIAC ARREST 117
LOWER RESPIRATORY TRACT INFECTION 114

Reactions in Hospitalization Reports

Hospitalization is HEAVY (10,339, 51.2% of the book). Top reactions in those rows:

Reaction Reports
PNEUMONIA 836
NAUSEA 741
DYSPNOEA 734
VOMITING 663
FALL 637
PYREXIA 625
DIARRHOEA 613
FATIGUE 591
CONSTIPATION 583
ASTHENIA 504
ACUTE KIDNEY INJURY 449
URINARY TRACT INFECTION 446
PAIN 416
SEPSIS 416
CONFUSIONAL STATE 408
ABDOMINAL PAIN 402
ANAEMIA 401
DEHYDRATION 397
MALAISE 397
HYPOTENSION 388
How to read senna FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)

FAERS holds 20,197 voluntary reports linked to senna (Senokot), 2004-2025. Death is listed on 3,098 (15.3%). Hospitalization appears on 10,339 (51.2%). Top co-reported indication: Product Used For Unknown Indication.

Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 51.2% mention hospitalization (10,339 reports).

Read with senna

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.