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Over-the-counter medicine

Sennosides

Sennosides is an over-the-counter medicine. No generic is listed; pharmacies paid $0.0258 per senna 8.6 mg tablet in the October 7, 2026 NADAC survey.

  • No generic listed
  • Over the counter

Check it at the source: the sennosides FDA label on DailyMed (effective May 30, 2024); every sennosides label on DailyMed.

Highlights of the record

FDA label of May 30, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026

Used for

From the label: indications and usage

Relieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours

Forms and strengths

  • 8.6 mg
  • 15 mg
  • 17.2 mg
  • 25 mg
  • 8.8 mg/5ml
  • 17.2 mg/17.21
  • 25 mg/15ml
  • 26.4 mg/15ml
  • 417.12 mg/237ml

Tablet; film-coated tablet; liquid; syrup; chewable tablet.

On the market

Generic approvals
No generic approved
Labelers listed (NDC)
96 of which 0 under generic applications, 0 under brand applications, repackagers included

Supply and safety

Pharmacy cost (NADAC)
$0.0258 per tablet Senna 8.6 mg tablet
Shortage (FDA)
No current entry
Recalls by its makers (FDA)
0 since 2013 0 Class I among all firms' recalls; 3 more by firms not listed as its makers
FAERS reports
41,594 through July 30, 2026

What is sennosides used for?

From the label: indications and usage

Relieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours

Conditions named in the indications of sennosides's FDA labels, with every medicine labeled for each:

From other sennosides labels

Constipation: Uses Relieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours

Source: FDA drug label (Senna), Patrin Pharma, Inc., effective May 30, 2024 (SPL set a9f1ef8d-8700-481f-a709-972bb9d27153), via openFDA; the full label on DailyMed

Is there a generic for sennosides?

No generic sennosides is approved (Drugs@FDA, October 8, 2026).

Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)

What do pharmacies pay for sennosides?

In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.0258 per Senna 8.6 mg tablet, up 4% from $0.0247 on October 8, 2025. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.

  • Senna 8.6 mg tablet (generic)
  • Senokot 8.6 mg tablet (brand)
$0.250
$0.021
January 2024October 2026
NADAC per unit, October 7, 2026
Strength and formBrand or genericPharmacy cost30 tablets, or one pen or vial12-month change
Chocolated laxativeGeneric$0.106 per unitn/a+0.4%
Ft senna laxative 8.6 mg tabletGeneric$0.0258 per tablet$0.774+4%
Gnp senna lax 8.6 mg tabletGeneric$0.0258 per tablet$0.774+4%
Laxative 15 mg tabletGeneric$0.0673 per tablet$2.02-0.5%
Laxative 25 mg tabletGeneric$0.116 per tablet$3.49no change
Qc laxative 8.6 mg tabletGeneric$0.0258 per tablet$0.774+4%
Senna 8.6 mg tabletGeneric$0.0258 per tablet$0.774+4%
Senna 8.8 mg/5 mL liquidGeneric$0.0369 per mLn/a-8%
Senna 8.8 mg/5 mL syrupGeneric$0.0369 per mLn/a-8%
Senna-lax 8.6 mg tabletGeneric$0.0258 per tablet$0.774+4%
Senna-time 8.6 mg tabletGeneric$0.0258 per tablet$0.774+4%
Sennosides 8.6 mg tabletGeneric$0.0258 per tablet$0.774n/a
Senokot 8.6 mg tabletBrand$0.247 per tablet$7.41+1%
Senokot extra str 17.2 mg tabletBrand$0.416 per tablet$12.49-0.1%

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

Has sennosides been recalled?

The FDA's Enforcement Report lists 3 recalls naming sennosides since 2013: 0 Class I (the most serious), 3 Class II, 0 Class III; 0 still ongoing. 3 of them are by firms that FDA's NDC Directory does not list as a maker of sennosides and that hold no application for it in Drugs@FDA, such as compounding pharmacies or bulk-ingredient suppliers; the recall notice names the product recalled. A recall names products and lots, not every product of the medicine.

StartedClassCompanyReason
May 7, 2018Class IIRIJ Pharmaceutical LLC not a listed makerCGMP Deviations: Products are being recalled due to an out of specification total aerobic microbial count in a water sample.
July 2, 2013Class IIAidapak Services, LLC not a listed makerLabeling:Label Mixup; SENNOSIDES Tablet, 8.6 mg may be potentially mislabeled as SACCHAROMYCES BOULARDII LYO, Capsule, 250 mg, NDC 00414200007, Pedigree …
July 2, 2013Class IIAidapak Services, LLC not a listed makerLabeling: Label Mixup: SENNOSIDES, Tablet, 8.6 mg may have potentially been mislabeled as one of the following drugs: FEXOFENADINE HCL, Tablet, 180 mg, NDC …

Source: FDA Enforcement Report (drug recalls) via openFDA, through October 8, 2026

What do FAERS reports show for sennosides?

The FDA Adverse Event Reporting System holds 41,594 reports that list sennosides among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 6,517 are coded as a death and 20,773 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Reports received each year

The most reported reactions

  • Fatigue3,646
  • Nausea3,133
  • Constipation (a use or a product term, not a reaction)3,006
  • Dyspnoea2,606
  • Diarrhoea2,513
  • Pain2,445
  • Death (an outcome recorded in the report)2,402
  • Pneumonia2,229

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026

What else is labeled for the same conditions as sennosides?

15 other medicines are given the same way (oral) and in the same FDA class as sennosides or labeled mainly for the same use (constipation), the same class first. Constipation lists all 20 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.

MedicineShared indicationGeneric labelers (oral)Pharmacy costShortage
DocusateConstipationnone listed$0.0276 per unit 100 mg softgelNo current entry
Polyethylene glycol 3350Constipation73 labelers$0.0286 per gram 3350 powdNo current entry
BisacodylConstipationnone listed$0.0441 per tablet 5 mg tabletNo current entry
Magnesium hydroxideConstipationnone listed$0.0095 per mL Milk of magnesia suspensionNo current entry
Magnesium citrateConstipationnone listed$0.0066 per mL Magnesium citrate solutionNo current entry
LubiprostoneConstipation10 labelers$0.651 per capsule 24 mcg capsuleNo current entry
PrucaloprideConstipation18 labelers$0.639 per tablet 1 mg tabletNo current entry
Psyllium huskConstipationnone listedn/aNo current entry

Every medicine labeled for the same conditions as sennosides

Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)

How does sennosides compare with medicines for the same use?

5 side-by-side pages set sennosides beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.

What next?

Alternatives to sennosides
15 medicines for the same use
Sennosides side effects
the label's list beside FAERS reports
Check an interaction
what two or more labels say about each other