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rasagiline Side Effects

Also known as: Azilect

Analysis of 3,152 adverse event reports submitted to the FDA from 2007 to 2025.

Total Reports

3,152

Death-Related

358

11.4% of reports

Hospitalizations

971

30.8% of reports

Top Indication

Parkinson^S Disease

Most Reported Adverse Reactions

FALL
343
HALLUCINATION
326
DYSKINESIA
276
DRUG INEFFECTIVE
272
PARKINSON^S DISEASE
216
DIZZINESS
205
TREMOR
204
DEATH
200
CONFUSIONAL STATE
178
DRUG INTERACTION
167
CONDITION AGGRAVATED
157
CONSTIPATION
154
GAIT DISTURBANCE
145
NAUSEA
141
FATIGUE
138
SOMNOLENCE
136
INSOMNIA
133
COUGH
132
PRODUCT DOSE OMISSION ISSUE
127
ANXIETY
125

Who Reports Side Effects

Gender Distribution

Female 1,048 (38%)
Male 1,722 (62%)

Age Distribution

0-17 18 (1%)
18-44 64 (3%)
45-64 500 (24%)
65-74 731 (35%)
75+ 748 (36%)

Reporting Trend by Year

2007 2025

Reactions in Death Reports

Top reactions reported in 358 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DEATH 200
HALLUCINATION 36
FALL 32
PARKINSON^S DISEASE 30
COMPLETED SUICIDE 21
PRODUCT DOSE OMISSION ISSUE 19
OFF LABEL USE 18
CONFUSIONAL STATE 17
DYSKINESIA 15
PNEUMONIA 15
DYSPHAGIA 13
URINARY TRACT INFECTION 13
ERECTILE DYSFUNCTION 12
DELUSION 11
CONDITION AGGRAVATED 10
ASTHENIA 9
DIARRHOEA 9
DRUG INEFFECTIVE FOR UNAPPROVED INDICATION 9
PRODUCT USE IN UNAPPROVED INDICATION 9
WEIGHT DECREASED 9

Reactions in Hospitalization Reports

Top reactions in 971 reports where hospitalization was an outcome.

Reaction Reports
FALL 208
DRUG INTERACTION 101
HALLUCINATION 94
DYSKINESIA 92
PARKINSON^S DISEASE 75
CONFUSIONAL STATE 74
SEROTONIN SYNDROME 69
GAIT DISTURBANCE 65
DIZZINESS 59
DYSPNOEA 54
CONDITION AGGRAVATED 53
URINARY TRACT INFECTION 52
DRUG INEFFECTIVE 48
ASTHENIA 47
OFF LABEL USE 47
CONSTIPATION 45
DELIRIUM 44
FATIGUE 44
MOBILITY DECREASED 43
TREMOR 43

Nearby — Related Medications

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What the FAERS Data Reveals About rasagiline Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 3,152 voluntary reports linked to rasagiline and its brand equivalents (Azilect), spanning 2007 through 2025. Of those, 358 (11.4%) listed death as an outcome and 971 (30.8%) involved hospitalization. The most common indication reported alongside adverse events was Parkinson^S Disease.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 38% were female and 62% male; age distribution skews toward 75+, with 748 reports in that bracket. The single most reported reaction is fall with 343 submissions, followed by hallucination and dyskinesia.

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice — speak with a licensed clinician about any side-effect concerns.