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Drug side effects

nadolol Side Effects

The reactions most often reported to the FDA for nadolol (also sold as Corgard), with demographics, serious outcomes, and reporting trends.

Data updated 2026-05-15

7,398
FAERS reports

Data from the FDA Adverse Event Reporting System (FAERS), 2004 to 2025. A FAERS report records a temporal association, not proof of cause. See our methodology for how figures are compiled and de-duplicated.

The most commonly reported side effects of nadolol come from 7,398 reports to the FDA, broken down here by frequency, patient demographics, and serious outcomes.

This page analyzes 7,398 reports to the FDA Adverse Event Reporting System (FAERS) for nadolol (Corgard): the reactions reported most often, who reported them, serious outcomes such as hospitalization, and year-over-year trends. A FAERS report does not prove the drug caused the effect, and report volume tracks how widely a drug is used, not how likely an effect is for any one person. Educational information, not medical advice.

Total Reports

7,398

Reports Mentioning Death

602

8.1% of reports — not proof the medicine caused the death

Hospitalizations

2,516

34.0% of reports

Top Indication

Product Used For Unknown Indication

Most Reported Adverse Reactions

MACULAR DEGENERATION
814
NAUSEA
663
HEADACHE
588
FATIGUE
522
PAIN
502
WEIGHT DECREASED
455
DIARRHOEA
433
MALAISE
412
PYREXIA
397
ANAEMIA
342
DIZZINESS
333
DYSPNOEA
319
ABDOMINAL PAIN
317
CONSTIPATION
305
THERAPEUTIC PRODUCT EFFECT INCOMPLETE
279
DYSPEPSIA
276
INFUSION RELATED REACTION
264
CHRONIC SINUSITIS
260

Who Reports Side Effects

Gender Distribution

Female 4,539 (66%)
Male 2,344 (34%)
Unknown 9

Age Distribution

0-17 218 (5%)
18-44 607 (13%)
45-64 1,881 (40%)
65-74 1,277 (27%)
75+ 714 (15%)

Reporting Trend by Year

2004 2025

Reactions in Death Reports

Top reactions reported in 602 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DEATH 199
COMPLETED SUICIDE 75
TOXICITY TO VARIOUS AGENTS 39
CARDIAC ARREST 32
RENAL FAILURE 31
HEPATIC FAILURE 29
PNEUMONIA 29
DYSPNOEA 28
HYPOTENSION 28
DIARRHOEA 27
FALL 27
ANAEMIA 26
FATIGUE 26
SEPTIC SHOCK 23
ASTHENIA 22
CONFUSIONAL STATE 21
GASTROINTESTINAL HAEMORRHAGE 21
PAIN 21
ANXIETY 19

Reactions in Hospitalization Reports

Top reactions in 2,516 reports where hospitalization was an outcome.

Reaction Reports
NAUSEA 382
PAIN 345
WEIGHT DECREASED 344
PYREXIA 324
MALAISE 314
HEADACHE 307
ANAEMIA 283
ABDOMINAL PAIN 260
THERAPEUTIC PRODUCT EFFECT INCOMPLETE 259
CHRONIC SINUSITIS 252
INFUSION RELATED REACTION 249
MACULAR DEGENERATION 243
RECTAL HAEMORRHAGE 243
PARAESTHESIA ORAL 233
DYSPEPSIA 232
CONSTIPATION 224
HAEMATOCHEZIA 220
PROCEDURAL PAIN 215

Compare nadolol vs acebutolol →

What the FAERS Data Reveals About nadolol Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 7,398 voluntary reports linked to nadolol and its brand equivalents (Corgard), spanning 2004 through 2025. Of those, 602 (8.1%) listed death as an outcome and 2,516 (34.0%) involved hospitalization. The most common indication reported alongside adverse events was Product Used For Unknown Indication.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 66% were female and 34% male; age distribution skews toward 45-64, with 1,881 reports in that bracket. The single most reported reaction is macular degeneration with 814 submissions, followed by nausea and headache.

How to read these numbers

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice, speak with a licensed clinician about any side-effect concerns.