LOW-VOLUME · SEX-BALANCED
guanfacine Side Effects
guanfacine (also sold as Intuniv, Tenex) is a LOW-VOLUME FAERS extract #355 of 524 by FAERS report count. Still opens on SEX-BALANCED: 37% of sex-coded reports are female (2,210 F / 3,811 M).
Data updated 2026-05-15
- 7,386
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
guanfacine reporting skew - 37% of sex-coded reports are female (2,210 F / 3,811 M). Volume band LOW-VOLUME #355 of 524 by FAERS report count; caseload WATCHLIST.
Thinner FAERS extract for guanfacine (Intuniv) (7,386 reports #355 of 524 by FAERS report count). 37% of sex-coded reports are female (2,210 F / 3,811 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
SOMNOLENCE leads 455 of 7,386 reports
Who reports · age peak 0-17 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 0-17 (3,034 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 228 reports (3.1% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 68 |
| DEATH | 51 |
| TOXICITY TO VARIOUS AGENTS | 31 |
| HYPOTENSION | 16 |
| COMA | 13 |
| GASTROINTESTINAL HAEMORRHAGE | 13 |
| TACHYCARDIA | 13 |
| RESPIRATORY DEPRESSION | 12 |
| DEPRESSED LEVEL OF CONSCIOUSNESS | 11 |
| ELECTROCARDIOGRAM QT PROLONGED | 11 |
| AGITATION | 10 |
| CARDIAC ARREST | 10 |
| DELIRIUM | 10 |
| DRUG INTERACTION | 10 |
| ELECTROCARDIOGRAM QRS COMPLEX PROLONGED | 10 |
| OVERDOSE | 10 |
| PARAESTHESIA | 10 |
| SUSPECTED SUICIDE | 10 |
| ASTHENIA | 9 |
Reactions in Hospitalization Reports
Hospitalization mid-share (1,757, 23.8%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| INTENTIONAL OVERDOSE | 181 |
| BRADYCARDIA | 175 |
| TOXICITY TO VARIOUS AGENTS | 169 |
| HYPOTENSION | 164 |
| SOMNOLENCE | 123 |
| OVERDOSE | 106 |
| DRUG INTERACTION | 99 |
| VOMITING | 92 |
| SUICIDE ATTEMPT | 89 |
| AGGRESSION | 84 |
| AGITATION | 83 |
| DIZZINESS | 78 |
| NAUSEA | 73 |
| ELECTROCARDIOGRAM QT PROLONGED | 72 |
| HYPERTENSION | 72 |
| SINUS BRADYCARDIA | 64 |
| CONDITION AGGRAVATED | 62 |
| HEADACHE | 62 |
How to read guanfacine FAERS figures (WATCHLIST · DEATH-MARKED · HOSP-MID)
FAERS holds 7,386 voluntary reports linked to guanfacine (Intuniv, Tenex), 2004-2025. Death is listed on 228 (3.1%). Hospitalization appears on 1,757 (23.8%). Top co-reported indication: Attention Deficit/Hyperactivity Disorder.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with guanfacine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 7,398 FAERS cases (Δ 12 heavier vs guanfacine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 7,404 FAERS cases (Δ 18 heavier vs guanfacine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 7,411 FAERS cases (Δ 25 heavier vs guanfacine); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 7,422 FAERS cases (Δ 36 heavier vs guanfacine); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 59.0 pp vs guanfacine's DEATH-MARKED): CASELOAD · HOSP-MID.
guanfacine stamps WATCHLIST · SEX-BALANCED; class peers and methodology beat restating the same FAERS caveats on every effects URL.