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glucagon Side Effects

Also known as: Baqsimi, GlucaGen

Analysis of 3,944 adverse event reports submitted to the FDA from 2004 to 2025.

Total Reports

3,944

Death-Related

654

16.6% of reports

Hospitalizations

1,898

48.1% of reports

Top Indication

Product Used For Unknown Indication

Most Reported Adverse Reactions

DRUG INEFFECTIVE
362
DYSPNOEA
354
ACUTE KIDNEY INJURY
313
HYPOTENSION
286
HYPOGLYCAEMIA
268
CONDITION AGGRAVATED
244
TOXICITY TO VARIOUS AGENTS
230
HAEMOPTYSIS
214
ANXIETY
213
NAUSEA
212
DEATH
209
PAIN IN EXTREMITY
202
BLOOD GLUCOSE DECREASED
193
BLOOD GLUCOSE INCREASED
193
VOMITING
191
ASTHMA
190
OFF LABEL USE
188
PNEUMONIA
180
HEADACHE
175
LUNG DISORDER
172

Who Reports Side Effects

Gender Distribution

Female 1,865 (52%)
Male 1,717 (48%)
Unknown 4

Age Distribution

0-17 205 (8%)
18-44 490 (19%)
45-64 923 (35%)
65-74 632 (24%)
75+ 394 (15%)

Reporting Trend by Year

2004 2025

Reactions in Death Reports

Top reactions reported in 654 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DEATH 208
ACUTE KIDNEY INJURY 135
DYSPNOEA 112
TOXICITY TO VARIOUS AGENTS 106
HAEMOPTYSIS 94
HYPOXIA 86
PRODUCTIVE COUGH 86
CONDITION AGGRAVATED 74
DRUG INEFFECTIVE 74
HYPOTENSION 73
PNEUMONIA 73
SEPSIS 68
ANXIETY 65
PAIN IN EXTREMITY 63
THROMBOSIS 62
ARTERIOSCLEROSIS 59
CARDIAC ARREST 59
HYPOTHYROIDISM 59
PULMONARY ALVEOLAR HAEMORRHAGE 59
PULMONARY FIBROSIS 59

Reactions in Hospitalization Reports

Top reactions in 1,898 reports where hospitalization was an outcome.

Reaction Reports
DYSPNOEA 248
HYPOTENSION 237
ACUTE KIDNEY INJURY 226
TOXICITY TO VARIOUS AGENTS 206
DRUG INEFFECTIVE 198
CONDITION AGGRAVATED 174
PNEUMONIA 163
HYPOXIA 153
INTENTIONAL OVERDOSE 152
HAEMOPTYSIS 151
PRODUCTIVE COUGH 142
ANXIETY 140
PAIN IN EXTREMITY 140
BRADYCARDIA 137
ASTHMA 124
HYPOGLYCAEMIA 124
PULMONARY EMBOLISM 124
VOMITING 124
LUNG DISORDER 114
HYPOTHYROIDISM 113

Nearby — Related Medications

Compare glucagon vs acarbose →

What the FAERS Data Reveals About glucagon Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 3,944 voluntary reports linked to glucagon and its brand equivalents (Baqsimi, GlucaGen), spanning 2004 through 2025. Of those, 654 (16.6%) listed death as an outcome and 1,898 (48.1%) involved hospitalization. The most common indication reported alongside adverse events was Product Used For Unknown Indication.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 52% were female and 48% male; age distribution skews toward 45-64, with 923 reports in that bracket. The single most reported reaction is drug ineffective with 362 submissions, followed by dyspnoea and acute kidney injury.

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice — speak with a licensed clinician about any side-effect concerns.