LOW-VOLUME · HOSP-HEAVY
propafenone Side Effects
propafenone (also sold as Rythmol) is a LOW-VOLUME FAERS extract #405 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 42.9% mention hospitalization (1,763 reports).
Data updated 2026-05-15
- 4,113
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
propafenone: 42.9% mention hospitalization (1,763 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #405 of 524 by FAERS report count.
Thinner FAERS extract for propafenone (Rythmol) (4,113 reports #405 of 524 by FAERS report count). 42.9% mention hospitalization (1,763 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ATRIAL FIBRILLATION leads 347 of 4,113 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (1,019 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (483 reports, 11.7%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 114 |
| DEATH | 87 |
| TOXICITY TO VARIOUS AGENTS | 61 |
| DRUG INTERACTION | 46 |
| CARDIAC ARREST | 40 |
| ACUTE KIDNEY INJURY | 32 |
| SUBARACHNOID HAEMORRHAGE | 29 |
| ELECTROCARDIOGRAM QRS COMPLEX PROLONGED | 27 |
| LOSS OF CONSCIOUSNESS | 26 |
| HYPOTENSION | 25 |
| NAUSEA | 24 |
| GASTROINTESTINAL HAEMORRHAGE | 23 |
| RESPIRATORY FAILURE | 21 |
| SEIZURE | 20 |
| ASTHENIA | 19 |
| COMA | 18 |
| DIARRHOEA | 18 |
| CARDIO-RESPIRATORY ARREST | 17 |
| ATRIAL FIBRILLATION | 16 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (1,763, 42.9% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| ATRIAL FIBRILLATION | 194 |
| DRUG INTERACTION | 158 |
| TOXICITY TO VARIOUS AGENTS | 151 |
| DYSPNOEA | 124 |
| NAUSEA | 109 |
| BRADYCARDIA | 108 |
| DIZZINESS | 107 |
| ASTHENIA | 105 |
| HYPOTENSION | 102 |
| ACUTE KIDNEY INJURY | 87 |
| FATIGUE | 84 |
| ELECTROCARDIOGRAM QRS COMPLEX PROLONGED | 82 |
| GASTROINTESTINAL HAEMORRHAGE | 78 |
| PNEUMONIA | 69 |
| VOMITING | 69 |
| CARDIAC ARREST | 67 |
| SYNCOPE | 67 |
| FALL | 64 |
How to read propafenone FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 4,113 voluntary reports linked to propafenone (Rythmol), 2004-2025. Death is listed on 483 (11.7%). Hospitalization appears on 1,763 (42.9%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with propafenone
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 4,135 FAERS cases (Δ 22 heavier vs propafenone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 4,083 FAERS cases (Δ 30 lighter vs propafenone); DEATH-RARE · HOSP-LIGHT · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 4,079 FAERS cases (Δ 34 lighter vs propafenone); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 4,175 FAERS cases (Δ 62 heavier vs propafenone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 50.4 pp vs propafenone's DEATH-HEAVY): CASELOAD · HOSP-MID.
propafenone stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.