HIGH-VOLUME · HOSP-HEAVY
fentanyl Side Effects
fentanyl (also sold as Duragesic, Actiq) is HIGH-VOLUME in this FAERS book #81 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 33.7% mention hospitalization (32,091 reports).
Data updated 2026-05-15
- 95,293
- FAERS reports
FAERS voluntary reports, 1997 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
fentanyl: 33.7% mention hospitalization (32,091 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #81 of 524 by FAERS report count.
High-report extract for fentanyl (Duragesic): 95,293 FAERS rows (1997-2025). Top named reactions: DRUG ABUSE, PAIN, DRUG DEPENDENCE. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1997–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DRUG ABUSE leads 10,453 of 95,293 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (22,231 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (27,119 reports, 28.5%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DRUG ABUSE | 8,949 |
| DEATH | 5,337 |
| TOXICITY TO VARIOUS AGENTS | 4,622 |
| OVERDOSE | 2,358 |
| CARDIO-RESPIRATORY ARREST | 1,526 |
| CARDIAC ARREST | 1,343 |
| DRUG DEPENDENCE | 1,259 |
| COMPLETED SUICIDE | 1,169 |
| RESPIRATORY ARREST | 874 |
| PAIN | 859 |
| RENAL FAILURE | 752 |
| PNEUMONIA | 712 |
| NAUSEA | 577 |
| MALIGNANT NEOPLASM PROGRESSION | 568 |
| SEPSIS | 568 |
| RESPIRATORY FAILURE | 558 |
| HYPOTENSION | 529 |
| DYSPNOEA | 526 |
| ANXIETY | 521 |
| VOMITING | 492 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (32,091, 33.7% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NAUSEA | 2,461 |
| PAIN | 2,239 |
| VOMITING | 2,084 |
| PNEUMONIA | 1,721 |
| DYSPNOEA | 1,697 |
| HYPOTENSION | 1,655 |
| DIARRHOEA | 1,633 |
| PYREXIA | 1,625 |
| FATIGUE | 1,608 |
| OVERDOSE | 1,415 |
| DRUG INTERACTION | 1,406 |
| FALL | 1,291 |
| TOXICITY TO VARIOUS AGENTS | 1,256 |
| ANAEMIA | 1,253 |
| DRUG ABUSE | 1,221 |
| ABDOMINAL PAIN | 1,196 |
| ASTHENIA | 1,159 |
| CONFUSIONAL STATE | 1,051 |
How to read fentanyl FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 95,293 voluntary reports linked to fentanyl (Duragesic, Actiq), 1997-2025. Death is listed on 27,119 (28.5%). Hospitalization appears on 32,091 (33.7%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with fentanyl
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 96,629 FAERS cases (Δ 1,336 heavier vs fentanyl); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 98,033 FAERS cases (Δ 2,740 heavier vs fentanyl); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 98,899 FAERS cases (Δ 3,606 heavier vs fentanyl); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 91,655 FAERS cases (Δ 3,638 lighter vs fentanyl); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 33.6 pp vs fentanyl's DEATH-HEAVY): CASELOAD · HOSP-MID.
fentanyl stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.