MID-VOLUME · HOSP-HEAVY
febuxostat Side Effects
febuxostat (also sold as Uloric) sits MID-VOLUME #263 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 42.7% mention hospitalization (6,835 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 16,005
- FAERS reports
FDA Adverse Event Reporting System extract for febuxostat. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
febuxostat: 42.7% mention hospitalization (6,835 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #263 of 524 by FAERS report count.
Mid-book FAERS page for febuxostat (Uloric) (16,005 reports). Signature HOSP-HEAVY. Dominant age band on file: 75+. Educational reference only.
Counts from the openFDA FAERS extract (2009–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DIARRHOEA leads 849 of 16,005 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (3,919 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (2,099 reports, 13.1%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 512 |
| PNEUMONIA | 166 |
| CARDIAC FAILURE | 134 |
| ACUTE KIDNEY INJURY | 128 |
| DYSPNOEA | 120 |
| PYREXIA | 114 |
| RESPIRATORY FAILURE | 102 |
| SEPSIS | 102 |
| RENAL FAILURE | 96 |
| ANAEMIA | 91 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 82 |
| PLATELET COUNT DECREASED | 81 |
| MALAISE | 77 |
| DIARRHOEA | 76 |
| CHRONIC KIDNEY DISEASE | 75 |
| DECREASED APPETITE | 75 |
| FEBRILE NEUTROPENIA | 75 |
| CARDIAC FAILURE CONGESTIVE | 64 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 61 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (6,835, 42.7% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| ACUTE KIDNEY INJURY | 555 |
| DIARRHOEA | 429 |
| ANAEMIA | 413 |
| PNEUMONIA | 411 |
| NAUSEA | 395 |
| DYSPNOEA | 393 |
| PYREXIA | 346 |
| RASH | 319 |
| FATIGUE | 311 |
| CARDIAC FAILURE | 306 |
| DECREASED APPETITE | 305 |
| HEADACHE | 296 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 275 |
| RENAL IMPAIRMENT | 270 |
| FALL | 262 |
| PAIN | 241 |
| ERYTHEMA | 237 |
| MALAISE | 237 |
How to read febuxostat FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 16,005 voluntary reports linked to febuxostat (Uloric), 2009-2025. Death is listed on 2,099 (13.1%). Hospitalization appears on 6,835 (42.7%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 42.7% mention hospitalization (6,835 reports).
Read with febuxostat
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 16,062 FAERS cases (Δ 57 heavier vs febuxostat); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 15,846 FAERS cases (Δ 159 lighter vs febuxostat); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 15,783 FAERS cases (Δ 222 lighter vs febuxostat); DEATH-MARKED · HOSP-LIGHT · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 16,231 FAERS cases (Δ 226 heavier vs febuxostat); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.0 pp vs febuxostat's DEATH-HEAVY): CASELOAD · HOSP-MID.
febuxostat stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.