MID-VOLUME · SEX-BALANCED
brexpiprazole Side Effects
brexpiprazole (also sold as Rexulti) sits MID-VOLUME #267 of 524 by FAERS report count. Lead signal: SEX-BALANCED - 69% of sex-coded reports are female (9,542 F / 4,320 M). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 15,755
- FAERS reports
FDA Adverse Event Reporting System extract for brexpiprazole. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-MID. How figures are compiled.
brexpiprazole reporting skew - 69% of sex-coded reports are female (9,542 F / 4,320 M). Volume band MID-VOLUME #267 of 524 by FAERS report count; caseload WATCHLIST.
Mid-book FAERS page for brexpiprazole (Rexulti) (15,755 reports). Signature SEX-BALANCED. Dominant age band on file: 18-44. Educational reference only.
Counts from the openFDA FAERS extract (2012–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
WEIGHT INCREASED leads 1,673 of 15,755 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (2,243 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (856 reports, 5.4%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 427 |
| COMPLETED SUICIDE | 120 |
| FALL | 50 |
| DISCOLOURED VOMIT | 43 |
| UNDERDOSE | 37 |
| CARDIAC FAILURE | 32 |
| RESPIRATORY ARREST | 31 |
| TREMOR | 28 |
| HALLUCINATION, AUDITORY | 25 |
| PNEUMONIA ASPIRATION | 25 |
| INTERNAL HAEMORRHAGE | 24 |
| CARDIAC ARREST | 18 |
| CARDIO-RESPIRATORY ARREST | 16 |
| DYSPHAGIA | 15 |
| MARASMUS | 15 |
| PNEUMONIA | 15 |
Reactions in Hospitalization Reports
Hospitalization mid-share (1,926, 12.2%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| SUICIDAL IDEATION | 217 |
| SUICIDE ATTEMPT | 163 |
| CONDITION AGGRAVATED | 161 |
| DEPRESSION | 126 |
| HOSPITALISATION | 116 |
| FALL | 101 |
| ANXIETY | 93 |
| FATIGUE | 83 |
| TREMOR | 80 |
| AKATHISIA | 77 |
| NAUSEA | 71 |
| TREATMENT NONCOMPLIANCE | 71 |
| ADVERSE DRUG REACTION | 70 |
| DIZZINESS | 70 |
| SOMNOLENCE | 70 |
| WEIGHT INCREASED | 69 |
| DRUG INTERACTION | 68 |
How to read brexpiprazole FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-MID)
FAERS holds 15,755 voluntary reports linked to brexpiprazole (Rexulti), 2012-2025. Death is listed on 856 (5.4%). Hospitalization appears on 1,926 (12.2%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-MID as signal-detection rates next to 69% of sex-coded reports are female (9,542 F / 4,320 M).
Read with brexpiprazole
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 15,757 FAERS cases (Δ 2 heavier vs brexpiprazole); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 15,783 FAERS cases (Δ 28 heavier vs brexpiprazole); DEATH-MARKED · HOSP-LIGHT · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 15,846 FAERS cases (Δ 91 heavier vs brexpiprazole); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 15,616 FAERS cases (Δ 139 lighter vs brexpiprazole); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 56.7 pp vs brexpiprazole's DEATH-HEAVY): CASELOAD · HOSP-MID.
brexpiprazole stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.