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benazepril Side Effects

Also known as: Lotensin

Analysis of 7,061 adverse event reports submitted to the FDA from 1998 to 2025.

Total Reports

7,061

Death-Related

572

8.1% of reports

Hospitalizations

2,464

34.9% of reports

Top Indication

Hypertension

Most Reported Adverse Reactions

NAUSEA
439
FATIGUE
408
DRUG INEFFECTIVE
398
DIZZINESS
382
DYSPNOEA
381
PAIN
361
DIARRHOEA
356
HEADACHE
344
MYOCARDIAL INFARCTION
310
HYPERTENSION
295
ASTHENIA
269
VOMITING
257
ANXIETY
253
CEREBROVASCULAR ACCIDENT
248
CARDIAC FAILURE CONGESTIVE
240
CHEST PAIN
239
RENAL FAILURE
239
ARTHRALGIA
233
COUGH
228
PRURITUS
226

Who Reports Side Effects

Gender Distribution

Female 3,723 (55%)
Male 3,019 (45%)
Unknown 8

Age Distribution

0-17 17 (0%)
18-44 321 (7%)
45-64 1,862 (42%)
65-74 1,197 (27%)
75+ 1,015 (23%)

Reporting Trend by Year

1998 2025

Reactions in Death Reports

Top reactions reported in 572 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DEATH 153
COMPLETED SUICIDE 81
MYOCARDIAL INFARCTION 63
RENAL FAILURE 63
PAIN 55
ANXIETY 50
CARDIAC ARREST 48
CARDIAC FAILURE CONGESTIVE 48
RESPIRATORY FAILURE 44
CEREBROVASCULAR ACCIDENT 43
INJURY 42
TOXICITY TO VARIOUS AGENTS 42
CARDIO-RESPIRATORY ARREST 40
DYSPNOEA 39
HYPOTENSION 39
NAUSEA 35
EMOTIONAL DISTRESS 31
FATIGUE 30
DIARRHOEA 28
MULTI-ORGAN FAILURE 28

Reactions in Hospitalization Reports

Top reactions in 2,464 reports where hospitalization was an outcome.

Reaction Reports
MYOCARDIAL INFARCTION 264
CARDIAC FAILURE CONGESTIVE 207
DYSPNOEA 203
CEREBROVASCULAR ACCIDENT 196
HYPERTENSION 175
CHEST PAIN 172
NAUSEA 171
PAIN 156
CORONARY ARTERY DISEASE 153
DIARRHOEA 148
ASTHENIA 146
FATIGUE 141
DIZZINESS 137
PNEUMONIA 136
FALL 135
VOMITING 131
RENAL FAILURE 127
ATRIAL FIBRILLATION 119
OEDEMA PERIPHERAL 111
HEADACHE 107

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What the FAERS Data Reveals About benazepril Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 7,061 voluntary reports linked to benazepril and its brand equivalents (Lotensin), spanning 1998 through 2025. Of those, 572 (8.1%) listed death as an outcome and 2,464 (34.9%) involved hospitalization. The most common indication reported alongside adverse events was Hypertension.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 55% were female and 45% male; age distribution skews toward 45-64, with 1,862 reports in that bracket. The single most reported reaction is nausea with 439 submissions, followed by fatigue and drug ineffective.

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice — speak with a licensed clinician about any side-effect concerns.