triazolam vs voriconazole
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Side-by-side comparison of triazolam and voriconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Other benzodiazepines including triazolam and alprazolam (CYP3A4 Inhibition) In Vitro Studies Demonstrated Potential for Voriconazole to Inhibit Metabolism (Increased Plasma Exposure) HMG-CoA Reductase Inhibitors (Statins) (CYP3A4 Inhibition) In Vitro Studies Demonstrated Potential for Voriconazole to Inhibit Metabolism (Increased Plasma Exposure) Frequent monitoring for adverse reactions and toxicity related to statins.
Halcion
Vfend
Triazolam (Halcion) is a medication used for the short-term treatment of insomnia. It belongs to a class of drugs called benzodiazepines, which help you fall asleep.
Voriconazole (Vfend) is an antifungal medicine. It is used to treat serious fungal infections in adults and children 2 years and older.
Triazolam is used to treat insomnia in adults. Insomnia is when you have trouble falling asleep or staying asleep. This medicine is only for short-term use, usually for 7 to 10 days.
This medicine treats several types of fungal infections. It is used for invasive aspergillosis, a lung infection. It also treats candidemia (a blood infection) and other Candida infections in the skin, abdomen, kidney, bladder, and wounds. Voriconazole can also treat esophageal candidiasis (a throat infection) and serious infections caused by Scedosporium and Fusarium fungi.
Triazolam works by slowing down activity in the brain. This helps you to relax and fall asleep. It affects certain chemicals in your brain called neurotransmitters.
Voriconazole belongs to a class of drugs called azole antifungals. It works by stopping the growth of fungi. It does this by interfering with the production of the fungal cell membrane.
- • Drowsiness
- • Headache
- • Dizziness
- • Nervousness
- • Light-headedness
- • Visual disturbances
- • Fever
- • Nausea
- • Rash
- • Vomiting
- Drug Abuse 519
- Sopor 402
- Nausea 352
- Overdose 350
- Fall 315
- Drug Interaction 2,315
- Death 1,460
- Pyrexia 1,411
- Pneumonia 1,321
- Condition Aggravated 1,093
Taking triazolam with opioid pain medicines can cause very serious problems, including slowed or stopped breathing, coma, and death. Because of these risks, doctors will only prescribe opioid pain medicines with triazolam when other treatment options are not sufficient. Do not misuse this medicine. Misuse can lead to addiction, overdose, or death. Stopping triazolam suddenly can cause dangerous withdrawal symptoms. Talk to your doctor before stopping this medicine.
Voriconazole can cause serious liver problems. Your doctor will check your liver function with blood tests before and during treatment. This medicine can also cause heart rhythm problems. Make sure your potassium, magnesium, and calcium levels are normal before starting. Voriconazole can also cause severe skin reactions and make you sensitive to sunlight. Avoid sunlight and wear protective clothing. This medicine can harm an unborn baby, so women who can get pregnant should use effective birth control.
Taking triazolam late in pregnancy may cause sedation or withdrawal symptoms in the newborn. If you are pregnant or plan to become pregnant, talk to your doctor about the risks and benefits of taking triazolam. A registry exists to track outcomes in women who take psychiatric medications, including triazolam, during pregnancy.
Voriconazole can cause harm to an unborn baby. If you are pregnant or could become pregnant, talk to your doctor. It is not known if voriconazole passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking this medicine.
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How to Read This triazolam vs voriconazole Comparison
triazolam is classified in the Benzodiazepine (Hypnotic) drug class, while voriconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, triazolam has 1,938 submissions while voriconazole has 7,600. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to voriconazole blocks the enzyme that processes triazolam, which can cause the drug to stay in your system longer. this leads to higher levels of the medication in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for triazolam or voriconazole.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.