lansoprazole vs voriconazole

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Side-by-side comparison of lansoprazole and voriconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Intervention : Voriconazole : See prescribing information.

Drug Class
lansoprazole Proton Pump Inhibitor (PPI)
voriconazole Azole Antifungal
Type
lansoprazole Over-the-Counter
voriconazole Prescription
Summary
lansoprazole

Lansoprazole is a medicine that reduces the amount of acid in your stomach. It belongs to a class of drugs called proton pump inhibitors (PPIs).

voriconazole

Voriconazole (Vfend) is an antifungal medicine. It is used to treat serious fungal infections in adults and children 2 years and older.

What It Treats
lansoprazole

Lansoprazole can treat several conditions caused by too much stomach acid. It can heal duodenal and gastric ulcers. It also treats heartburn (GERD) and a damaged esophagus (erosive esophagitis).

voriconazole

This medicine treats several types of fungal infections. It is used for invasive aspergillosis, a lung infection. It also treats candidemia (a blood infection) and other Candida infections in the skin, abdomen, kidney, bladder, and wounds. Voriconazole can also treat esophageal candidiasis (a throat infection) and serious infections caused by Scedosporium and Fusarium fungi.

How It Works
lansoprazole

Lansoprazole works by blocking the enzyme in the stomach that produces acid. This helps to lower the amount of acid made. Lowering acid helps to heal damage and relieve symptoms.

voriconazole

Voriconazole belongs to a class of drugs called azole antifungals. It works by stopping the growth of fungi. It does this by interfering with the production of the fungal cell membrane.

Common Side Effects
lansoprazole
  • Diarrhea
  • Abdominal pain
  • Nausea
  • Constipation
voriconazole
  • Visual disturbances
  • Fever
  • Nausea
  • Rash
  • Vomiting
FAERS Reports
lansoprazole
  • Chronic Kidney Disease 32,775
  • Acute Kidney Injury 18,670
  • Renal Failure 13,811
  • End Stage Renal Disease 9,782
  • Renal Injury 9,520
voriconazole
  • Drug Interaction 2,315
  • Death 1,460
  • Pyrexia 1,411
  • Pneumonia 1,321
  • Condition Aggravated 1,093
Serious Warnings
lansoprazole

Lansoprazole may hide the symptoms of stomach cancer. If you have a poor response or early return of symptoms, your doctor may do more tests. Long-term use of PPIs like lansoprazole may increase your risk of bone fractures. It may also cause low magnesium levels or Vitamin B-12 deficiency.

voriconazole

Voriconazole can cause serious liver problems. Your doctor will check your liver function with blood tests before and during treatment. This medicine can also cause heart rhythm problems. Make sure your potassium, magnesium, and calcium levels are normal before starting. Voriconazole can also cause severe skin reactions and make you sensitive to sunlight. Avoid sunlight and wear protective clothing. This medicine can harm an unborn baby, so women who can get pregnant should use effective birth control.

Pregnancy
lansoprazole

Talk to your doctor if you are pregnant or plan to become pregnant. Lansoprazole may affect bone development in the fetus. If you take lansoprazole with clarithromycin, also consider clarithromycin's pregnancy risks.

voriconazole

Voriconazole can cause harm to an unborn baby. If you are pregnant or could become pregnant, talk to your doctor. It is not known if voriconazole passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking this medicine.

Also Compare, Nearby Drugs

How to Read This lansoprazole vs voriconazole Comparison

lansoprazole is classified in the Proton Pump Inhibitor (PPI) drug class, while voriconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, lansoprazole has 84,558 submissions while voriconazole has 7,600. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to voriconazole can stop your body from breaking down lansoprazole as quickly as it should. this can cause the amount of lansoprazole in your blood to increase.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for lansoprazole or voriconazole.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.