itraconazole vs meloxicam

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Side-by-side comparison of itraconazole and meloxicam. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Nonsteroidal Anti-Inflammatory Drugs Meloxicam a Concomitant drug dose increase may be necessary.

Drug Class
itraconazole Azole Antifungal
meloxicam Nonsteroidal Anti-Inflammatory Drug (NSAID)
Type
itraconazole Prescription
meloxicam Prescription
Summary
itraconazole

Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.

meloxicam

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID). It helps to reduce pain and swelling.

What It Treats
itraconazole

Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.

meloxicam

Meloxicam treats the symptoms of osteoarthritis and rheumatoid arthritis. It can also treat juvenile rheumatoid arthritis in children who weigh at least 132 pounds (60 kg). This medicine helps to relieve pain, swelling, and stiffness in your joints.

How It Works
itraconazole

Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.

meloxicam

Meloxicam works by reducing substances in the body that cause pain and inflammation. It blocks the production of prostaglandins. Prostaglandins contribute to inflammation and pain.

Common Side Effects
itraconazole
  • Nausea
  • Rash
  • Headache
meloxicam
  • Diarrhea
  • Upper respiratory infection
  • Upset stomach
  • Flu-like symptoms
FAERS Reports
itraconazole
  • Drug Interaction 1,118
  • Pyrexia 568
  • Dyspnoea 474
  • Pneumonia 461
  • Nausea 445
meloxicam
  • Pain 4,670
  • Fatigue 4,578
  • Arthralgia 4,222
  • Nausea 3,807
  • Headache 3,323
Serious Warnings
itraconazole

Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.

meloxicam

Meloxicam may increase your risk of serious heart problems, including heart attack and stroke, which can be fatal. This risk may occur early in treatment and may increase with longer use. You should not take meloxicam if you are having heart bypass surgery. Meloxicam can also increase your risk of serious stomach and intestinal problems, including bleeding, ulcers, and holes, which can be fatal. These problems can occur without warning. The elderly and those with a history of ulcers are at greater risk.

Pregnancy
itraconazole

You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.

meloxicam

Using meloxicam between 20 and 30 weeks of pregnancy may cause kidney problems in the baby, leading to low amniotic fluid. Avoid using meloxicam after 30 weeks of pregnancy because it can cause heart problems in the baby. Talk to your doctor if you are pregnant or plan to become pregnant.

Also Compare, Nearby Drugs

How to Read This itraconazole vs meloxicam Comparison

itraconazole is classified in the Azole Antifungal drug class, while meloxicam sits within the Nonsteroidal Anti-Inflammatory Drug (NSAID) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, itraconazole has 3,066 submissions while meloxicam has 20,600. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to itraconazole may cause the level of meloxicam in your blood to decrease, which could make the pain reliever less effective.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for itraconazole or meloxicam.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.