insulin degludec vs olanzapine

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Side-by-side comparison of insulin degludec and olanzapine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Drugs That May Decrease the Blood Glucose Lowering Effect of XULTOPHY 100/3.6 Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones.

Drug Class
insulin degludec Ultra-Long-Acting Insulin
olanzapine Atypical Antipsychotic
Type
insulin degludec Prescription
olanzapine Prescription
Summary
insulin degludec

No summary available.

olanzapine

Olanzapine is a medicine used to treat certain mental disorders. It helps to balance chemicals in the brain to improve mood and behavior.

What It Treats
insulin degludec

Information not available.

olanzapine

Olanzapine is used to treat schizophrenia in adults and teens (13-17). It also treats manic or mixed episodes of bipolar I disorder in adults and teens (13-17). In adults, it can be used with other medicines to treat bipolar depression.

How It Works
insulin degludec

Information not available.

olanzapine

Olanzapine is an atypical antipsychotic. It works by affecting the levels of certain chemicals in your brain. These chemicals include dopamine and serotonin, which can help improve mood, thinking, and behavior.

Common Side Effects
insulin degludec
  • Common cold
  • Headache
  • Feeling sick to your stomach
  • Diarrhea
  • Increased lipase (an enzyme)
olanzapine
  • Dizziness
  • Weight gain
  • Increased appetite
  • Dry mouth
  • Constipation
FAERS Reports
insulin degludec
  • Blood Glucose Increased 3,617
  • Nausea 1,381
  • Blood Glucose Decreased 1,252
  • Vomiting 894
  • Hypoglycaemia 886
olanzapine
  • Weight Increased 6,722
  • Diabetes Mellitus 5,388
  • Drug Interaction 4,048
  • Toxicity To Various Agents 3,966
  • Somnolence 3,839
Serious Warnings
insulin degludec

No specific warnings noted.

olanzapine

Olanzapine can increase the risk of death in older adults with dementia-related psychosis. Olanzapine is not approved to treat this condition. When using olanzapine with fluoxetine, read the Symbyax label for more warnings.

Pregnancy
insulin degludec

No pregnancy information available.

olanzapine

If you take olanzapine during the third trimester of pregnancy, your baby may have withdrawal symptoms after birth. There is a pregnancy registry to monitor outcomes in women who take atypical antipsychotics during pregnancy. Talk to your doctor.

Also Compare, Nearby Drugs

How to Read This insulin degludec vs olanzapine Comparison

insulin degludec is classified in the Ultra-Long-Acting Insulin drug class, while olanzapine sits within the Atypical Antipsychotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, insulin degludec has 8,030 submissions while olanzapine has 23,963. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to olanzapine can reduce the ability of insulin to lower your blood sugar. this can result in higher blood sugar levels.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for insulin degludec or olanzapine.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.