fluconazole vs suvorexant
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Side-by-side comparison of fluconazole and suvorexant. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
The recommended dose of BELSOMRA is 5 mg in subjects receiving moderate CYP3A inhibitors (e.g., amprenavir, aprepitant, atazanavir, ciprofloxacin, diltiazem, erythromycin, fluconazole, fosamprenavir, grapefruit juice, imatinib, verapamil).
Diflucan
Belsomra
Fluconazole is an antifungal medicine. It is used to treat infections caused by fungus.
Belsomra is a prescription medicine used to treat insomnia. It helps you fall asleep and stay asleep.
Fluconazole treats vaginal yeast infections. It also treats yeast infections in the mouth and esophagus. Fluconazole can also treat urinary tract infections, peritonitis, systemic Candida infections, and pneumonia. It can also treat cryptococcal meningitis. Fluconazole can also prevent candidiasis in patients undergoing bone marrow transplantation.
Belsomra is used to treat insomnia in adults. Insomnia means you have trouble falling asleep, staying asleep, or both. This medicine can help you sleep better.
Fluconazole works by stopping the growth of fungi. It blocks the fungus from producing a substance it needs to grow. This helps to clear up the infection.
Belsomra works by blocking orexin, a chemical in your brain that keeps you awake. By blocking orexin, Belsomra helps to reduce wakefulness and allows you to fall asleep.
- • Headache
- • Nausea
- • Abdominal pain
- • Sleepiness
- Pyrexia 4,121
- Nausea 3,697
- Diarrhoea 3,538
- Fatigue 3,151
- Pain 3,123
- Nightmare 736
- Somnolence 726
- Insomnia 674
- Abnormal Dreams 599
- Headache 535
Coadministration of other drugs known to prolong the QT interval and which are metabolized via the enzyme CYP3A4 such as erythromycin, pimozide, and quinidine are contraindicated in patients receiving fluconazole.
Belsomra can cause you to feel sleepy during the day and can impair your ability to drive. Do not drive or do other activities that require you to be fully alert, especially if you take the 20 mg dose. Belsomra may also worsen depression or cause suicidal thoughts. Tell your doctor right away if you have any new or worsening mood changes. Complex sleep behaviors like sleepwalking have also been reported. Stop taking Belsomra and tell your doctor if this happens.
Tell your doctor if you are pregnant or plan to become pregnant. Fluconazole may not be safe for your baby. Talk to your doctor about breastfeeding while taking fluconazole.
It is not known if Belsomra can harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if Belsomra passes into breast milk. Talk to your doctor about the best way to feed your baby if you take Belsomra.
Also Compare, Nearby Drugs
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How to Read This fluconazole vs suvorexant Comparison
fluconazole is classified in the Azole Antifungal drug class, while suvorexant sits within the Orexin Receptor Antagonist class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, fluconazole has 17,630 submissions while suvorexant has 3,270. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to fluconazole blocks the enzyme that clears suvorexant from your system, making the sleep medicine stay in your body longer.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for fluconazole or suvorexant.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.