fluconazole vs meloxicam
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Side-by-side comparison of fluconazole and meloxicam. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Although not specifically studied, fluconazole has the potential to increase the systemic exposure of other non-steroidal anti-inflammatory drugs (NSAIDs) that are metabolized by CYP2C9 (e.g., naproxen, lornoxicam, meloxicam, diclofenac).
Diflucan
Mobic
Fluconazole is an antifungal medicine. It is used to treat infections caused by fungus.
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID). It helps to reduce pain and swelling.
Fluconazole treats vaginal yeast infections. It also treats yeast infections in the mouth and esophagus. Fluconazole can also treat urinary tract infections, peritonitis, systemic Candida infections, and pneumonia. It can also treat cryptococcal meningitis. Fluconazole can also prevent candidiasis in patients undergoing bone marrow transplantation.
Meloxicam treats the symptoms of osteoarthritis and rheumatoid arthritis. It can also treat juvenile rheumatoid arthritis in children who weigh at least 132 pounds (60 kg). This medicine helps to relieve pain, swelling, and stiffness in your joints.
Fluconazole works by stopping the growth of fungi. It blocks the fungus from producing a substance it needs to grow. This helps to clear up the infection.
Meloxicam works by reducing substances in the body that cause pain and inflammation. It blocks the production of prostaglandins. Prostaglandins contribute to inflammation and pain.
- • Headache
- • Nausea
- • Abdominal pain
- • Diarrhea
- • Upper respiratory infection
- • Upset stomach
- • Flu-like symptoms
- Pyrexia 4,121
- Nausea 3,697
- Diarrhoea 3,538
- Fatigue 3,151
- Pain 3,123
- Pain 4,670
- Fatigue 4,578
- Arthralgia 4,222
- Nausea 3,807
- Headache 3,323
Coadministration of other drugs known to prolong the QT interval and which are metabolized via the enzyme CYP3A4 such as erythromycin, pimozide, and quinidine are contraindicated in patients receiving fluconazole.
Meloxicam may increase your risk of serious heart problems, including heart attack and stroke, which can be fatal. This risk may occur early in treatment and may increase with longer use. You should not take meloxicam if you are having heart bypass surgery. Meloxicam can also increase your risk of serious stomach and intestinal problems, including bleeding, ulcers, and holes, which can be fatal. These problems can occur without warning. The elderly and those with a history of ulcers are at greater risk.
Tell your doctor if you are pregnant or plan to become pregnant. Fluconazole may not be safe for your baby. Talk to your doctor about breastfeeding while taking fluconazole.
Using meloxicam between 20 and 30 weeks of pregnancy may cause kidney problems in the baby, leading to low amniotic fluid. Avoid using meloxicam after 30 weeks of pregnancy because it can cause heart problems in the baby. Talk to your doctor if you are pregnant or plan to become pregnant.
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How to Read This fluconazole vs meloxicam Comparison
fluconazole is classified in the Azole Antifungal drug class, while meloxicam sits within the Nonsteroidal Anti-Inflammatory Drug (NSAID) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, fluconazole has 17,630 submissions while meloxicam has 20,600. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to fluconazole blocks the enzymes that break down this pain medicine, which can cause the medicine to build up in your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for fluconazole or meloxicam.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.