budesonide/formoterol vs itraconazole
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Side-by-side comparison of budesonide/formoterol and itraconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
Caution should be exercised when considering the coadministration of SYMBICORT with long-term ketoconazole and other known strong CYP3A4 inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin) [see Warnings and Precautions (5.9) ] .
Symbicort
Sporanox
Symbicort is a combination medicine that contains a steroid and a long-acting bronchodilator. It helps to control asthma and COPD symptoms.
Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.
Symbicort is used to treat asthma in people 6 years and older. It can help control asthma long-term. Symbicort 160/4.5 is also used to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It helps to improve airflow and reduce flare-ups.
Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.
Symbicort contains two medicines. Budesonide reduces inflammation in the lungs. Formoterol relaxes the muscles around your airways, making it easier to breathe.
Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.
- • Nasopharyngitis (common cold)
- • Headache
- • Upper respiratory tract infection
- • Sore throat
- • Sinusitis
- • Nausea
- • Rash
- • Headache
- Difficulty breathing 6,363
- Asthma 4,697
- Tiredness 3,354
- Cough 3,164
- Headache 2,978
- Drug Interaction 1,118
- Pyrexia 568
- Dyspnoea 474
- Pneumonia 461
- Nausea 445
Long-acting beta-agonists (LABAs) like formoterol may increase the risk of asthma-related death if used alone. Do not use Symbicort to treat sudden asthma symptoms. Symbicort can also increase your risk of pneumonia, especially if you have COPD. Tell your doctor if you have signs of pneumonia like fever, cough, or increased mucus production.
Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Symbicort will harm your unborn baby. Discuss the risks and benefits with your doctor. It is also not known if Symbicort passes into breast milk.
You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.
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How to Read This budesonide/formoterol vs itraconazole Comparison
budesonide/formoterol is classified in the Corticosteroid / Long-Acting Beta-2 Agonist Combination drug class, while itraconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, budesonide/formoterol has 20,556 submissions while itraconazole has 3,066. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to itraconazole blocks the enzyme that breaks down the steroid part of this inhaler. this can lead to higher levels of the medicine in your body than intended.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for budesonide/formoterol or itraconazole.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.