anidulafungin vs micafungin
PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.
Side-by-side comparison of anidulafungin and micafungin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
Eraxis
Mycamine
Eraxis is an antifungal medicine. It treats certain Candida infections in your body.
Micafungin is an antifungal medicine. It treats certain Candida infections in adults and children.
Eraxis treats candidemia and other Candida infections, like intra-abdominal abscesses and peritonitis. It can be used in adults and children 1 month and older. Eraxis also treats esophageal candidiasis (a Candida infection in the esophagus) in adults. However, Eraxis may not work as well for esophageal candidiasis, and the infection may come back.
Micafungin treats several types of Candida infections. These include infections in the blood, abdomen, and esophagus. It can also prevent Candida infections in stem cell transplant patients.
Eraxis belongs to a class of drugs called echinocandins. It works by stopping the growth of the fungus Candida. It does this by blocking a key part of the fungal cell wall.
Micafungin stops the growth of Candida by blocking a key part of its cell wall. This weakens the fungus and allows your body to fight the infection. It targets a substance called 1,3-beta-D-glucan.
- • Low potassium levels
- • Nausea
- • Diarrhea
- • Vomiting
- • Fever
- • Diarrhea
- • Nausea
- • Vomiting
- • Abdominal pain
- • Fever
- Multiple Organ Dysfunction Syndrome 171
- Septic Shock 127
- Sepsis 115
- Pneumonia 94
- Pyrexia 90
- Pyrexia 281
- Febrile Neutropenia 258
- Multiple Organ Dysfunction Syndrome 213
- Acute Kidney Injury 204
- Respiratory Failure 193
Eraxis can cause liver problems. Your doctor should check your liver function while you are taking Eraxis. Allergic reactions, including shock, can happen. Tell your doctor right away if you have any signs of an allergic reaction, like rash, hives, flushing, itching, trouble breathing, or low blood pressure. Eraxis contains fructose. If you have hereditary fructose intolerance, you should not take Eraxis.
Micafungin can cause serious allergic reactions, including shock. Tell your doctor right away if you have hives, trouble breathing, or swelling. It can also cause liver problems. Your doctor will check your liver function during treatment.
Eraxis may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Eraxis passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding while taking Eraxis.
Micafungin may harm your unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if micafungin passes into breast milk. Talk to your doctor about the risks and benefits of breastfeeding.
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How to Read This anidulafungin vs micafungin Comparison
anidulafungin is classified in the Echinocandin Antifungal drug class, while micafungin sits within the Echinocandin Antifungal class. Because both drugs share the same classification, they are often considered interchangeable in theory, but clinical outcomes rarely track that cleanly. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, anidulafungin has 597 submissions while micafungin has 1,149. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for anidulafungin or micafungin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.